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中华脑血管病杂志(电子版) ›› 2023, Vol. 17 ›› Issue (04) : 386 -393. doi: 10.11817/j.issn.1673-9248.2023.04.014

临床病例研究

复合手术治疗椎动脉慢性闭塞一例
陆东生, 桂建康, 范衍, 刘春林, 李祉岑, 宫崧峰()   
  1. 518035 深圳市第二人民医院神经外科血管病区
  • 收稿日期:2022-12-18 出版日期:2023-08-01
  • 通信作者: 宫崧峰
  • 基金资助:
    深圳市第二人民医院临床研究项目(20223357038)

Hybrid surgery for chronic vertebral artery occlusion: a case report

Dongsheng Lu, Jiankang Gui, Yan Fan, Chunlin Liu, Zhicen Li, Songfeng Gong()   

  1. Department of Neurosurgery, Shenzhen Second People's Hospital, Shenzhen 518035, China
  • Received:2022-12-18 Published:2023-08-01
  • Corresponding author: Songfeng Gong
引用本文:

陆东生, 桂建康, 范衍, 刘春林, 李祉岑, 宫崧峰. 复合手术治疗椎动脉慢性闭塞一例[J]. 中华脑血管病杂志(电子版), 2023, 17(04): 386-393.

Dongsheng Lu, Jiankang Gui, Yan Fan, Chunlin Liu, Zhicen Li, Songfeng Gong. Hybrid surgery for chronic vertebral artery occlusion: a case report[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(04): 386-393.

目的

总结复合手术治疗椎动脉闭塞的策略和手术疗效。

方法

回顾性分析1例由深圳市第二人民医院神经外科血管病区收治的椎动脉慢性闭塞患者的临床资料,经脑血管造影检查发现右侧椎动脉近端闭塞,左侧椎动脉中段闭塞。采用传统椎动脉内膜剥脱术联合血管内介入支架植入术开通一侧闭塞椎动脉。术后定期随访。

结果

通过复合手术(先行颈部椎动脉血管切开和内膜剥脱,后行介入支架植入术)顺利开通一侧闭塞椎动脉(椎动脉近端闭塞侧),术后患者各项临床表现明显较术前有所改善,术后1个月、3个月、术后半年以及术后1年均返院复查头颈部CT血管造影,提示复合手术治疗-侧椎动脉闭塞再通良好,血管通畅。术后随访提示患者各项临床表现也明显较术前有所好转。

结论

对于椎动脉近端闭塞患者,进行复合手术治疗既能从根本上剥离闭塞椎动脉内膜,也能通过植入支架支撑血管,防止血管二次闭塞,比传统单纯椎动脉内膜剥脱或单纯介入支架植入术有更明显优势,手术效果良好。

Objective

To summarize the strategy and surgical efficacy of hybrid surgery for vertebral artery occlusion.

Methods

A retrospective analysis of the clinical diagnosis of a patient with right proximal vertebral artery occlusion, left middle vertebral artery occlusion, and initial stenosis which was found by cerebral angiography in the Neurosurgery Vascular Ward of Shenzhen Second People's Hospital. Traditional vertebral endarterectomy combined with interventional vertebral artery occlusion and stenting was used to open one side of the occluded vertebral artery, and regular postoperative follow-up was performed.

Results

Through hybrid surgery (first cervical vertebral artery vascular incision and endarterectomy, followed by interventional stent implantation), one side of the occluded vertebral artery (the proximal vertebral artery occlusion side) was successfully opened, and the postoperative clinical manifestations of the patients were significantly improved. The preoperative improvement was improved, and the head and neck computer technology angiography examinations at 1 month, 3 months ,half a year and even one year after the operation indicated that the lateral vertebral artery occlusion was well recanalized and the vertebral artery blood vessels were unobstructed. Postoperative follow-up showed that the clinical manifestations of the patients were also significantly improved compared with those before surgery.

Conclusion

For patients with proximal vertebral artery occlusion, hybrid surgery can not only fundamentally strip the intima of the occluded vertebral artery, but also support the blood vessel by inserting a stent to prevent the risk of secondary occlusion of the blood vessel. Compared with simple interventional stent implantation, it has obvious advantages, and this surgical method has good surgical outcomes during follow-up.

图1 患者术前不同时间段头颈部血管CTA+CTP检查(头颈部动脉+脑组织血流灌注成像)。图a 2021年5月21日头颈部CTA正面观,可见双侧椎动脉重度狭窄并闭塞可能;红色箭头示右侧椎动脉V1~V2段重度狭窄(接近闭塞);蓝色箭头示左侧椎动脉V2~V4段闭塞。图b 2021年8月3日头颈部CTA检查,可见双侧椎动脉重度狭窄并闭塞可能,但左侧椎动脉闭塞情况较前好转;红色箭头示右侧椎动脉V1~V2段重度狭窄(闭塞可能);蓝色箭头示左侧椎动脉V2~V4段闭塞情况较前好转。图c 2021年8月5日脑血管造影检查,提示右侧椎动脉近段未显影,中远段通过右侧甲颈干动脉代偿显影良好;蓝色箭头示右侧椎动脉近端呈节段性闭塞。图d 2021年8月5日脑血管造影检查,提示左侧椎动脉远段闭塞,通过脊髓动脉多支分支动脉代偿;蓝色箭头示左侧椎动脉远段闭塞可能。图e 2021年8月10日头颈部CTA+CTP检查,双侧椎动脉狭窄并闭塞可能;红色箭头示右侧椎动脉V1~V2段闭塞可能;蓝色箭头示左侧椎动脉狭窄情况较前明显好转
图2 复合手术(椎动脉内膜剥脱+支架球囊扩张后联合支架植入术)术中的具体操作过程图示。图a术前右椎动脉内膜剥脱开口标识位置。图b椎动脉局部解剖位置;红色箭头示右侧颈动脉的解剖位置;蓝色箭头示右侧椎动脉的局部解剖位置(V1~V2段)。图c右侧椎动脉内膜剥脱的进一步进程;红色箭头示右侧颈动脉局部解剖位置;蓝色箭头示右侧椎动脉慢性闭塞性粥样斑块的内膜。图d右侧椎动脉内膜剥脱术后的即刻造影图像;蓝色箭头示右侧椎动脉近端血流通畅欠佳,仅有起始部一小段。图e运用临时阻断夹阻断锁骨下动脉,微导丝及微导管顺利开通闭塞椎动脉;蓝色箭头示临时阻断夹位置。图f右侧椎动脉介入球囊从远到近逐步扩张椎动脉的术中造影图像。图g介入球囊扩张后等待15 min后椎动脉部分管腔再次狭窄;蓝色箭头示椎动脉管腔再发狭窄。图h行介入椎动脉由远到近的支架植入;蓝色箭头示椎动脉支架位置。图i右侧椎动脉介入球囊扩张+介入支架植入术后造影图像;蓝色箭头示右侧椎动脉近端支架植入,椎动脉血管通畅良好
图3 复合手术(椎动脉内膜剥脱+支架球囊扩张后联合支架植入术)术后复查影像资料图示。图a(CPR图像):术后3 d复查头颈部CTA,检查提示,右椎动脉呈术后改变,血流通畅良好;蓝色箭头示右侧椎动脉术后的局部解剖位置结构(V1~V2段)以及支架植入位置。图b(VRT图像):椎动脉支架植入术后改变,可见椎动脉支架外观及血管管壁钙化情况;蓝色箭头示右侧椎动脉支架植入位置情况。图c(CPR图像):术后3个月复查头颈部CTA,检查提示,右侧椎动脉呈术后改变,血流通畅良好,近端局部血流通畅程度稍欠佳;蓝色箭头示右侧椎动脉术后改变以及支架植入位置
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