切换至 "中华医学电子期刊资源库"

中华脑血管病杂志(电子版) ›› 2020, Vol. 14 ›› Issue (05) : 300 -302. doi: 10.11817/j.issn.1673-9248.2020.05.010

所属专题: 经典病例 文献

病例报告

免疫抑制患者并发带状疱疹脑膜血管炎一例
洪月慧1, 关鸿志1, 黎波2, 刘霜2, 彭斌1,()   
  1. 1. 100730 中国医学科学院北京协和医学院,北京协和医院神经科
    2. 100730 中国医学科学院北京协和医学院,北京协和医院急诊科
  • 收稿日期:2020-06-10 出版日期:2020-10-01
  • 通信作者: 彭斌
  • Received:2020-06-10 Published:2020-10-01
引用本文:

洪月慧, 关鸿志, 黎波, 刘霜, 彭斌. 免疫抑制患者并发带状疱疹脑膜血管炎一例[J]. 中华脑血管病杂志(电子版), 2020, 14(05): 300-302.

图1 右侧颈动脉造影示右大脑前动脉A1段节段性狭窄(红色箭头)
图2 头MRI平扫示右侧基底节、侧脑室旁新发梗死灶、DWI高信号(红色箭头),左侧基底节异常信号扩大、DWI不高(蓝色箭头)。图a、c为液体衰减反转恢复序列(FLAIR),图b、d为弥散加权成像(DWI)
图3 脑脊液下一代测序 基因组覆盖度为23.40%,检出水痘-带状疱疹病毒核酸序列拷贝数267个,占检出病原的97.09%
1
Steiner I, Kennedy PG, Pachner AR. The neurotropic herpes viruses: herpes simplex and varicella-zoster [J]. Lancet Neurol, 2007,6(11): 1015-1028.
2
Gilden D, Cohrs RJ, Mahalingam R, et al. Varicella zoster virus vasculopathies: diverse clinical manifestations, laboratory features, pathogenesis, and treatment [J]. Lancet Neurol, 2009, 8(8): 731-740.
3
Gilden DH, Kleinschmidt-DeMasters BK, LaGuardia JJ, et al. Neurologic complications of the reactivation of varicella-zoster virus [J]. N Engl J Med, 2000, 342(9): 635-645.
4
Oxman MN. Immunization to reduce the frequency and severity of herpes zoster and its complications [J]. Neurology, 1995, 45(12 Suppl 8): S41-S46.
5
Galil K, Choo PW, Donahue JG, et al. The sequelae of herpes zoster [J]. Arch Intern Med, 1997, 157(11): 1209-1213.
6
Marra F, Ruckenstein J, Richardson K. A meta-analysis of stroke risk following herpes zoster infection [J]. BMC Infect Dis, 2017, 17(1): 198.
7
Breuer J, Pacou M, Gautier A, et al. Herpes zoster as a risk factor for stroke and TIA: a retrospective cohort study in the UK [J]. Neurology, 2014, 83(2): e27-e33.
8
关鸿志, 宋红梅, 崔丽英. 开启脑炎诊疗的精准医学之门 [J]. 中华儿科杂志, 2017, 55(11): 801-804.
9
Guan H, Shen A, Lv X, et al. Detection of virus in CSF from the cases with meningoencephalitis by next-generation sequencing [J]. J Neurovirol, 2016, 22(2): 240-245.
10
吕遐, 关鸿志, 吴红龙, 等. 新一代测序在中枢神经系统感染病原体检测中的应用 [J]. 中华神经科杂志, 2016, 49(9): 737-740.
11
Solomon T, Michael BD, Smith PE, et al. Management of suspected viral encephalitis in adults--Association of British Neurologists and British Infection Association National Guidelines [J]. J Infect, 2012, 64(4): 347-373.
No related articles found!
阅读次数
全文


摘要