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中华脑血管病杂志(电子版) ›› 2025, Vol. 19 ›› Issue (06) : 562 -565. doi: 10.3877/cma.j.issn.1673-9248.2025.06.017

病例报告

强化药物治疗下出现卒中复发伴斑块内出血一例及文献复习
周汶丽, 蓝琳芳, 赵惠杰, 黄学文, 范玉华()   
  1. 510080 广东 广州,中山大学附属第一医院神经科
  • 收稿日期:2025-08-27 出版日期:2025-12-01
  • 通信作者: 范玉华
  • 基金资助:
    国家自然科学基金青年项目(81901187); 广州科技大脑计划(2023A04J2193)

Recurrent stroke with intraplaque hemorrhage despite intensive medical treatment: a case report and literature review

Wenli Zhou, Linfang Lan, Huijie Zhao   

  • Received:2025-08-27 Published:2025-12-01
引用本文:

周汶丽, 蓝琳芳, 赵惠杰, 黄学文, 范玉华. 强化药物治疗下出现卒中复发伴斑块内出血一例及文献复习[J/OL]. 中华脑血管病杂志(电子版), 2025, 19(06): 562-565.

Wenli Zhou, Linfang Lan, Huijie Zhao. Recurrent stroke with intraplaque hemorrhage despite intensive medical treatment: a case report and literature review[J/OL]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2025, 19(06): 562-565.

图1 首次卒中时患者头颅影像学检查结果。图a为头颈CT血管成像,箭头示左侧大脑中动脉M1段近端重度狭窄;图b为CT灌注成像,见左侧大脑半球灌注减低,达峰时间(TTP)延长;图c为弥散加权成像,见左侧半卵圆中心新近梗死;图d~f为血管壁高分辨磁共振成像不同序列,箭头示左侧大脑中动脉M1段近端偏心斑块,伴明显强化,未见斑块内出血 注:T1WI为T1加权成像;T2WI为T2加权成像;T1+C为T1增强序列。白色方框内为红色箭头所指局部放大图
图2 卒中复发时患者头颅影像学检查结果。图a为弥散加权成像,见左侧放射冠新近梗死;图b为头颈CT血管成像,箭头示左侧大脑中动脉M1段闭塞,远端分支较前减少;图c为CT灌注成像,见左侧大脑中动脉供血区灌注进一步减低,达峰时间(TTP)明显延长;图d~f为血管壁高分辨磁共振成像不同序列图像,箭头示左侧大脑中动脉M1段管壁T1加权成像呈高信号,提示新发斑块内出血,未见明显强化 注:T1WI为T1加权成像;T2WI为T2加权成像;T1+C为T1增强序列。白色方框内为红色箭头所指局部放大图
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