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Chinese Journal of Cerebrovascular Diseases(Electronic Edition) ›› 2020, Vol. 14 ›› Issue (02): 100-103. doi: 10.11817/j.issn.1673-9248.2020.02.008

Special Issue:

• Original Article • Previous Articles     Next Articles

Clinical efficacy of solo transcatheter closure of patent foramen ovale guided by transthoracic echocardiography

Wenjun Zhou1, Jin Lin1, Xinpeng Jiang1, Hang Yang1, Yichen Gong1, Yuanhao Fu1, Qingli Sun1, Yu Fu1, Xiaogang Li1, Jieli Feng1, Xinhang Feng1, Xiaoming Li1,(), Zhe Zhang1,()   

  1. 1. Department of Cardiosurgery, Peking University Third Hospital, Beijing 100191, China
  • Received:2020-02-19 Online:2020-04-01 Published:2020-04-01
  • Contact: Xiaoming Li, Zhe Zhang
  • About author:
    Corresponding author: Zhang Zhe, Email:
    Li xiaoming, Email:

Abstract:

Objective

To observe the safety and efficacy of solo transcatheter closure of Patent Foramen Ovale (PFO) guided solely by transthoracic echocardiography (TTE).

Methods

A total of 25 cases were retrospectively included who underwent the solo transcatheter closure of PFO guided by TTE in Peking University Third Hospital from December 2018 to December 2019. They were 20 females and 5 males with average age of (42.3±7.8) years. TTE was performed immediately after percutaneous closure. The follow-up interviews were conducted at 1 month, 3 months, and 6 months after the procedure, respectively. There were 6 patients with cryptogenic stroke (RoPE score>6) and 19 patients with obstinate migraine. The presence of PFO was confirmed by preoperative transesophageal echocardiography (TEE). The diameter of PFO was 2-3 mm and the diameter of tunnel was 4-8 mm. The contrast-enhanced transcranial doppler (cTCD) was 2-3 grade.

Results

All patients were successfully treated with the solo transcatheter closure of PFO guided by TTE. The mean procedural time (from puncture to sheath removal) was (32.1±7.5) mins. During the operation, 3 cases presented vagal reflex and 2 cases developed transient ventricular arrhythmia, which disappeared after conservative treatment. All patients were discharged the next day after operation without complications, e.g. pericardial effusion, peripheral vascular injury, or cardiac perforation. During the follow-ups, no patients suffered from pericardial effusion, occluder malposition, residual shunt, recurrence of headache and stroke. The cTCD is normal.

Conclusion

The solo transcatheter closure of PFO guided by TTE is an effective procedure with high successful rate and low rate of complications.

Key words: Patent foramen ovale, Transthoracic echocardiography, Transcatheter closure

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