Progress in the association between uric acid and ischemic stroke

doi:10.11817/j.issn.1673-9248.2021.03.002

Abstract

Abstract:

Uric acid (UA) is the end product of purine nucleotide metabolism. Previous studies found that UA was associated with ischemic stroke. On the other hand, UA is the major endogenous antioxidant, which may reduce oxidative stress in ischemic stroke patients. Some studies suggested that UA therapy during acute phase of ischemic stroke could improve patients’ outcome. However, the association between UA and ischemic stroke and its prognosis remains unclear. Investigating the above association and its underlying mechanisms is of great clinical significance, which may help clinicians to make appropriate treatment and prevention measures.

Key words: Uric acid, Ischemic stroke, Morbidity, Prognosis

Changyi Wang, Bo Wu. Progress in the association between uric acid and ischemic stroke[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2021, 15(03): 135-139.

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