Effect of comprehensive intervention on controlling risk factors in high-risk stroke population in community

doi:10.11817/j.issn.1673-9248.2022.05.007

Abstract

Abstract:

Objective

To observe the effect of comprehensive intervention on controlling risk factors in high-risk stroke population in community.

Methods

In January 2020, 120 persons with high-risk of stroke were included to participate in the study in Shanyang Town, Jinshan District, Shanghai. They were randomly divided into comprehensive intervention group (60 subjects) and general intervention group (60 subjects). The comprehensive intervention group was given lifestyle intervention, psychological intervention, carotid ultrasound examination (subjects with carotid artery plaques were given primary preventive medication), management for hypertension, diabetes and dyslipidemia, regular follow-ups, and health education. The general intervention group only received one casual telephone follow-up within one year, simple health education and guidance. After 1 years of intervention, t-test was used to compare the systolic blood pressure, diastolic blood pressure, blood glucose, glycosylated hemoglobin, cholesterol, low density lipoprotein, body mass index（BMI）and the stroke health knowledge evaluation score between the two groups; χ²-test of rates of the two samples was used to compare the healthy lifestyle rate, carotid ultrasound examination rate and carotid plaque drug treatment rate between the two groups.

Results

After 1 years of intervention, the systolic blood pressure [(126.20±6.75)mmHg vs (137.40±13.07)mmHg, t=5.915, P＜0.001], diastolic blood pressure [(74.65±7.58)mmHg vs (80.13±10.15)mmHg, t=3.353, P=0.001], blood glucose [(5.89±0.83)mmol/L vs (6.82±1.62)mmol/L, t=3.991, P＜0.001], glycosylated hemoglobin [(6.21±0.59)% vs (6.78±1.46)%, t=2.802, P=0.006], cholesterol [(4.08±0.78)mmol/L vs (4.96±1.53)mmol/L, t=3.989, P＜0.001], low density lipoprotein [(2.33±0.75) mmol/L vs (3.03±1.23) mmol/L, t=3.757, P＜0.001], BMI (23.76±1.41 vs 26.47±3.19, t=6.029, P＜0.001) in the comprehensive intervention group were lower than those in the general intervention group. The stroke health knowledge evaluation score (79.77±8.63 vs 52.50±12.61, t=13.820, P＜0.001), rate of healthy lifestyle (68.33% vs 10.00%, χ²=48.676, P＜0.001), carotid ultrasound examination rate (93.33% vs 46.67%, χ²=31.110, P＜0.001), and drug treatment rate of carotid plaque (100.00% vs 84.21%, χ²=4.007, P=0.045) in the comprehensive intervention group were higher than those in the general intervention group.

Conclusion

Comprehensive intervention can effectively control the risk factors in high-risk stroke population in community, improving their stroke health knowledge and promoting a healthy lifestyle.

Key words: Stroke, Cerebrovascular disease, Risk factors, Comprehensive intervention, Community

Jingquan Qu, Yang Yu, Jialian Wu, Jian Chen, Junjie Hao. Effect of comprehensive intervention on controlling risk factors in high-risk stroke population in community[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2022, 16(05): 326-331.

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References 30

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组别	例数	胆固醇（mmol/L）			低密度脂蛋白（mmol/L）			BMI
组别	例数	干预前	干预后		干预前	干预后		干预前	干预后
综合干预组	60	5.48±0.91	4.08±0.78^a		3.41±0.74	2.33±0.75^a		25.12±2.79	23.76±1.41^a
普通干预组	60	5.23±1.64	4.96±1.53^b		3.23±1.29	3.03±1.23^b		26.43±3.35	26.47±3.19^b
t值		1.058	3.989		0.942	3.757		2.280	6.029
P值		0.292	＜0.001		0.348	＜0.001		0.024	＜0.001
组别	例数	收缩压（mmHg）		舒张压（mmHg）		血糖（mmol/L）		糖化血红蛋白（%）
组别	例数	干预前	干预后	干预前	干预后	干预前	干预后	干预前	干预后
综合干预组	60	152.90±14.34	126.20±6.75^a	84.42±12.70	74.65±7.58^a	7.41±1.78	5.89±0.83^a	7.17±1.31	6.21±0.59^a
普通干预组	60	149.90±15.92	137.40±13.07^a	84.45±13.33	80.13±10.15^b	7.04±2.16	6.82±1.62^b	6.93±1.52	6.78±1.46^b
t值		1.103	5.915	0.014	3.353	1.013	3.991	0.939	2.802
P值		0.272	＜0.001	0.989	0.001	0.305	＜0.001	0.350	0.006

组别	例数	胆固醇（mmol/L）			低密度脂蛋白（mmol/L）			BMI
组别	例数	干预前	干预后		干预前	干预后		干预前	干预后
综合干预组	60	5.48±0.91	4.08±0.78^a		3.41±0.74	2.33±0.75^a		25.12±2.79	23.76±1.41^a
普通干预组	60	5.23±1.64	4.96±1.53^b		3.23±1.29	3.03±1.23^b		26.43±3.35	26.47±3.19^b
t值		1.058	3.989		0.942	3.757		2.280	6.029
P值		0.292	＜0.001		0.348	＜0.001		0.024	＜0.001
组别	例数	收缩压（mmHg）		舒张压（mmHg）		血糖（mmol/L）		糖化血红蛋白（%）
组别	例数	干预前	干预后	干预前	干预后	干预前	干预后	干预前	干预后
综合干预组	60	152.90±14.34	126.20±6.75^a	84.42±12.70	74.65±7.58^a	7.41±1.78	5.89±0.83^a	7.17±1.31	6.21±0.59^a
普通干预组	60	149.90±15.92	137.40±13.07^a	84.45±13.33	80.13±10.15^b	7.04±2.16	6.82±1.62^b	6.93±1.52	6.78±1.46^b
t值		1.103	5.915	0.014	3.353	1.013	3.991	0.939	2.802
P值		0.272	＜0.001	0.989	0.001	0.305	＜0.001	0.350	0.006

组别	人数	干预前	干预后	t值	P值
综合干预组	60	47.97±13.51	79.77±8.63	15.360	＜0.001
普通干预组	60	48.27±13.50	52.50±12.61	1.775	0.078
t值		0.122	13.820
P值		0.903	＜0.001

组别	人数	干预前	干预后	t值	P值
综合干预组	60	47.97±13.51	79.77±8.63	15.360	＜0.001
普通干预组	60	48.27±13.50	52.50±12.61	1.775	0.078
t值		0.122	13.820
P值		0.903	＜0.001

组别	人数	干预前	干预后	χ²值	P值
综合干预组	60	4（8.33）	41（68.33）	48.676	＜0.001
普通干预组	60	4（8.33）	6（10.00）	0.436	0.509
χ²值		＜0.001	48.676
P值		1.000	＜0.001

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