Research progress on the mechanism of mild hypothermia therapy for cerebral infarction

doi:10.11817/j.issn.1673-9248.2023.05.016

Abstract

Abstract:

Mild hypothermia therapy had been recommended for acute massive cerebral infarction. In recent years, there has been some research progress on the mechanism of mild hypothermia therapy on cerebral infarction, including anti-apoptosis, maintenance of mitochondrial function, regulation of autophagy, regulation of expression of non-coding RNA, and anti-inflammation effect. In order to promote the application of mild hypothermia therapy in the treatment of cerebral infarction, this paper reviewed the research progress on the mechanism of mild hypothermia therapy.

Key words: Mild hypothermia therapy, Cerebral infarction, Cell apoptosis, Autophagy, Mitochondria, Non-coding RNA

Tian Qiu, Miaojuan Yang, Bo Hu, Yi Guo, Yitao He. Research progress on the mechanism of mild hypothermia therapy for cerebral infarction[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(05): 518-521.

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