To study the efficiency of manual compression with small dosage thrombin injection for treating the patients with iatrogenic femoral pseudoaneurysm after cerebrovascular interventional therapy under ultrasound guidance.

A total of 13 patients suffering from post-cerebrovascular interventional therapy iatrogenic femoral pseudoaneurysm at Beijing Hospital of Traditional Chinese Medicine from July 2017 to June 2022 were analyzed including 10 male and 3 female. At first, the body, the neck, and the blood supply area of pseudoaneurysm were located by ultrasonography. The skin puncturing point of nearest to pseudoaneurysm body was marker. 20 gauge needle with thrombin was punctured into the center of the pseudoaneurysm, with the dosage of 1-2 ml, solution concentration 200 U/ml. The speed was slow and the injection stopped when the tumor cavity was filled about 80%-90%. Manual Compression was conducted for 5-10 mins followed by bandage compression. The patients were in a horizontal position for 24 hours. Ultrasonography was performed at 24 hours and 2 months after the operation in all patients, respectively.

12 patients (92.3%) were treated successfully at one time. The other one patient (7.7%) was injected twice to succeed and the other one patient (7.7%) had an allergic reaction. All the patients needed to take oral antiplatelet drugs (Aspirin or Clopidogrel), and followed-up for 2 months. The pseudoaneurysm did not recur. And the overall success rate was 100%, with satisfactory the efficiency.

Manual compression with small dosage thrombin injection for treating the patients of iatrogenic femoral pseudoaneurysm under ultrasound guidance is a safe and effective method, which has high clinical application value.