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Chinese Journal of Cerebrovascular Diseases(Electronic Edition) ›› 2024, Vol. 18 ›› Issue (05): 510-515. doi: 10.11817/j.issn.1673-9248.2024.05.018

• Review • Previous Articles    

Clinical progress of sitting intolerance in children

Yali Cao1,2,3, Yumeng Gao1, Yingqian Zhang2,3, Bo Li2,3, Junbao Du1, Hongfang Jin1,4,()   

  1. 1.Department of Pediatrics, Peking University First Hospital, Beijing 100034,China
    2.Department of Cardiology, Hebei Province Children's Hospital, Shijiazhuang 050031, China
    3.Hebei Key Laboratory of Pediatric cardiovascular disease, Shijiazhuang 050031, China
    4.Key Laboratory of Vascular Homeostasis and Remodeling, Beijing 100191, China
  • Received:2024-07-08 Online:2024-10-01 Published:2024-11-25
  • Contact: Hongfang Jin

Abstract:

Sitting intolerance is a group of clinical syndromes associated with postural change,particularly when transitioning from a supine to a sitting position or during periods of sedentary behavior.The main manifestations include dizziness, headache, blurred vision, palpitations, and chest tightness, with syncope potentially occurring in severe instances. Its frequent attacks will seriously affect the quality of life,and overall well-being of children. In 2020, the two types of children's sitting intolerance, sitting tachycardia syndrome and sitting hypertension, were proposed for the first time. Up to date, the understanding of sitting intolerance diseases in children has been still at the initial stage. This review has introduced the classification,diagnosis, possible pathophysiological mechanisms, risk factors, differential diagnosis, and treatment of sitting intolerance in children, aiming to improve the knowledge of sitting intolerance in children among pediatric healthcare professionals, arouse more attention to sitting intolerance in children, and improve the diagnosis and treatment of sitting intolerance.

Key words: Sitting intolerance, Diagnosis, Pathophysiological mechanism, Risk factor, Children

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