The outcomes of cardiac arrest (CA) patients are still not optimistic. Severe brain damage after resuscitation is the main cause of death and neurological disability. Therefore, reducing brain injury is the key point of treatment in post CA syndrome. Target temperature management (TTM) is proved to be the only intervention that can effectively improve survival and neurological prognosis. However, a investigation published recently showed insufficient understanding and poor practice of TTM in CA patients in China. So it is of great significance to promote TTM awareness and translations of guidelines into standardized clinical practice in pre-hospital emergency medical systems, departments of emergency, intensive care units. We comprehensively interpreted the TTM part in 2020 expert consensus statement on neuroprotection after cardiac arrest in China and other international guidelines, mainly involved the neuroprotective mechanism, timing of initiation, target temperature, duration of the cooling phase, cooling methods and rewarming rate.