To compare the clinical efficacy of the stent retriever with that of the a direct aspiration first pass technique（ADAPT）in the treatment of acute ischemic stroke with cerebral artery occlusions.

The clinical data of 40 patients who underwent mechanical thrombectomy in our hospital from Aug 2019 to Dec 2020 were retrospectively selected and divided into two groups. Among them, 19 patients were treated with stent retrievers, and the other 21 patients were treated with ADAPT. The success rate of recanalization, operation time, NIHSS score, thrombosis escape rate, postoperative cerebral hemorrhage rate, the proportion of good prognosis at one month after the operation, and postoperative mortality were compared between the two groups.

There was no significant difference in coronary heart disease, cerebral arterial stenosis, hypertension, diabetes, and major postoperative complication between the two groups (P＞0.05). There was no significant difference in the success rate of recanalization [89.5% (17/19) vs 85.7% (18/21)], operation time [(96.8±16.2) min vs (93.0±13.5) min], NIHSS score [(5.6±4.6) score vs (5.8±4.1) score], thrombosis escape rate [10.5% (2/19) vs 4.8%(1/21)], postoperative cerebral hemorrhage rate [15.8% (3/19) vs 4.8% (1/21)], the proportion of good prognosis at one month after operation [52.6% (10/19) vs 47.6% (10/21)], and postoperative mortality [26.3% (5/19) vs 14.3% (3/21)] between the two groups (P=1.00; t=0.828, P=0.413; t=187.5, P=0.752; P=0.596; P=0.331; P=1.000; P=0.442).

Both the stent retriever and ADAPT have good clinical efficacy in the treatment of acute ischemic stroke with cerebral artery occlusions.