切换至 "中华医学电子期刊资源库"

中华脑血管病杂志(电子版) ›› 2022, Vol. 16 ›› Issue (01) : 17 -21. doi: 10.11817/j.issn.1673-9248.2022.01.004

专家论坛

头颈部磁共振血管成像新技术及其在动脉粥样硬化斑块中的应用研究进展
张归玲1, 汤翔宇1, 张顺1, 朱文珍1,()   
  1. 1. 430030 武汉,华中科技大学同济医学院附属同济医院放射科
  • 收稿日期:2020-12-01 出版日期:2022-02-01
  • 通信作者: 朱文珍
  • 基金资助:
    国家自然科学基金重点项目(81730049)

New head and neck vascular magnetic resonance techniques and their application in atherosclerotic plaque

Guiling Zhang1, Xiangyu Tang1, Shun Zhang1, Wenzhen Zhu1,()   

  1. 1. Department of Radiology, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China
  • Received:2020-12-01 Published:2022-02-01
  • Corresponding author: Wenzhen Zhu
引用本文:

张归玲, 汤翔宇, 张顺, 朱文珍. 头颈部磁共振血管成像新技术及其在动脉粥样硬化斑块中的应用研究进展[J/OL]. 中华脑血管病杂志(电子版), 2022, 16(01): 17-21.

Guiling Zhang, Xiangyu Tang, Shun Zhang, Wenzhen Zhu. New head and neck vascular magnetic resonance techniques and their application in atherosclerotic plaque[J/OL]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2022, 16(01): 17-21.

随着磁共振技术的发展,越来越多的血管新技术涌现,在血管的形态学及血流动力学检测和研究中发挥着重要的作用。头颈部斑块是血管最常见的疾病。斑块破裂导致的脑卒中具有高致残率和病死率。本文总结了近些年新兴的磁共振技术,包括高分辨磁共振血管壁成像、4D flow磁共振成像、静音磁共振血管成像及压缩感知磁共振血管成像,介绍其成像原理及其在斑块疾病中的研究进展或应用前景。

With the development of magnetic resonance technology, more new vascular techniques are emerging and play an important role in vascular morphology and hemodynamics. The plaque in head and neck is the most common vascular pathology. Plaque rupture may lead to stroke which is a disease with high disability and mortality. We summarizes the new techniques including high resolution magnetic resonance of vessel wall imaging, 4D flow magnetic resonance imaging, silent magnetic resonance angiography and compressed sensing magnetic resonance angiography; and introduced the imaging principle and their applications in plaque.

1
Jia Q, Zhao X, Wang C, et al. Diabetes and poor outcomes within 6 months after acute ischemic stroke: the China National Stroke Registry [J]. Stroke, 2011, 42(10): 2758-2762.
2
Liu L, Wang D, Wong KS, et al. Stroke and stroke care in China: huge burden, significant workload, and a national priority [J]. Stroke, 2011, 42(12): 3651-3654.
3
Wong LK. Global burden of intracranial atherosclerosis [J]. Int J Stroke, 2006, 1(3): 158-159.
4
Gorelick PB, Wong KS, Bae HJ, et al. Large artery intracranial occlusive disease: a large worldwide burden but a relatively neglected frontier [J]. Stroke, 2008, 39(8): 2396-2399.
5
Clarke R, Du H, Kurmi O, et al. Burden of carotid artery atherosclerosis in Chinese adults: Implications for future risk of cardiovascular diseases [J]. Eur J Prev Cardiol, 2017, 24(6): 647-656.
6
Naghavi M, Libby P, Falk E, et al. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: part I [J]. Circulation, 2003, 108(14): 1664-1672.
7
吴平生, 张远慧, 许乙凯, 等. 易损斑块及易损患者的新定义及危险分层 [J]. 中华心血管病杂志, 2014, 32(3): 283-285.
8
中华医学会外科学分会血管外科学组. 颈动脉狭窄诊治指南 [J/CD]. 中国血管外科杂志(电子版), 2017, 9(3): 169-175.
9
Mandell DM, Mossa-Basha M, Qiao Y, et al. Intracranial vessel wall MRI: principles and expert consensus recommendations of the American Society of Neuroradiology [J]. AJNR Am J Neuroradiol, 2017, 38(2): 218-229.
10
Yuan C, Mitsumori LM, Ferguson MS, et al. In vivo accuracy of multispectral magnetic resonance imaging for identifying lipid-rich necrotic cores and intraplaque hemorrhage in advanced human carotid plaques [J]. Circulation, 2001, 104(17): 2051-2056.
11
Wasserman BA, Smith WI, Trout HH, et al. Carotid artery atherosclerosis: in vivo morphologic characterization with gadolinium-enhanced double-oblique MR imaging-initial results [J]. Radiology, 2002, 223(2): 566-573.
12
Liang J, Liu Y, Xu X, et al. Cerebral perforating artery disease: characteristics on high-resolution magnetic resonance imaging [J]. Clin Neuroradiol, 2019, 29(3): 533-541.
13
Klein IF, Lavallee PC, Mazighi M, et al. Basilar artery atherosclerotic plaques in paramedian and lacunar pontine infarctions: a high-resolution MRI study [J]. Stroke, 2010, 41(7): 1405-1409.
14
Chung JW, Kim BJ, Sohn CH, et al. Branch atheromatous plaque: a major cause of lacunar infarction (high-resolution MRI study) [J]. Cerebrovasc Dis Extra, 2012, 2(1): 36-44.
15
Qiao Y, Etesami M, Astor BC, et al. Carotid plaque neovascularization and hemorrhage detected by MR imaging are associated with recent cerebrovascular ischemic events [J]. AJNR Am J Neuroradiol, 2012, 33(4): 755-760.
16
Qiao Y, Zeiler SR, Mirbagheri S, et al. Intracranial plaque enhancement in patients with cerebrovascular events on high-spatial-resolution MR images [J]. Radiology, 2014, 271(2): 534-542.
17
Wang EL, Shao S, Li S, et al. A high-resolution MRI study of the relationship between plaque enhancement and ischemic stroke events in patients with intracranial atherosclerotic stenosis [J]. Front Neurol, 2019, 9: 1154.
18
Ma X, Zhao Q, Zhao L, et al. In vivo MR imaging of plaque disruption and thrombus formation in an atherosclerotic rabbit model [J]. Int J Cardiovasc Imaging, 2012, 28(3): 577-586.
19
Choi YJ, Jung SC, Lee DH. Vessel wall imaging of the intracranial and cervical carotid arteries [J]. J Stroke, 2015, 17(3): 238-255.
20
彭雯佳, 陆建平. 动脉粥样硬化管壁的多对比高分辨率MRI研究进展 [J]. 中华放射学杂志, 2015, 49(8): 637-640.
21
Yuan C, Petty C, O'Brien KD, et al. In vitro and in situ magnetic resonance imaging signal features of atherosclerotic plaque-associated lipids [J]. Arterioscler Thromb Vasc Biol, 1997, 17(8): 1496-1503.
22
Toussaint JF, LaMuraglia GM, Southern JF, et al. Magnetic resonance images lipid, fibrous, calcified, hemorrhagic, and thrombotic components of human atherosclerosis in vivo [J]. Circulation, 1996, 94(5): 932-938.
23
Markl M, Frydrychowicz A, Kozerke S, et al. 4D flow MRI [J]. J Magn Reson Imaging, 2012, 36(5): 1015-1036.
24
Wu C, Schnell S, Vakil P, et al. In vivo assessment of the impact of regional intracranial atherosclerotic lesions on brain arterial 3D hemodynamics [J]. AJNR Am J Neuroradiol, 2017, 38(3): 515-522.
25
Markl M, Wegent F, Zech T, et al. In vivo wall shear stress distribution in the carotid artery: effect of bifurcation geometry, internal carotid artery stenosis, and recanalization therapy [J]. Circ Cardiovasc Imaging, 2010, 3(6): 647-655.
26
Wehrum T, Gunther F, Kams M, et al. Quantification of aortic stiffness in stroke patients using 4D flow MRI in comparison with transesophageal echocardiography [J]. Int J Cardiovas Imaging, 2018, 34(10): 1629-1636.
27
Markl M, Brendecke SM, Simon J, et al. Co-registration of the distribution of wall shear stress and 140 complex plaques of the aorta [J]. Magn Reson Imaging, 2013, 31(7): 1156-1162.
28
Zhang G, Wang Z, Zhang S, et al. Age and anatomical location related hemodynamic changes assessed by 4D flow MRI in the carotid arteries of healthy adults [J]. Eur J Radiol, 2020, 128: 109035.
29
Eshtehardi P, Teng Z. Protective or destructive: high wall shear stress and atherosclerosis [J]. Atherosclerosis, 2016, 251:501-503.
30
Eshtehardi P, Brown AJ, Bhargava A, et al. High wall shear stress and high-risk plaque: an emerging concept [J]. Int J Cardiovasc Imaging, 2017, 33(7): 1089-1099.
31
赵扬, 王敬时, 王伟, 等. 基于压缩感知的磁共振血管快速成像的研究进展 [J]. 医疗卫生装备, 2016, 37(3): 104-109.
32
Cukur T, Lustig M, Nishimura DG. Improving non-contrast-enhanced steady-state free precession angiography with compressed sensing [J]. Magn Reson Med, 2009, 61(5): 1122-1131.
33
Li B, Li H, Dong L, et al. Fast carotid artery MR angiography with compressed sensing based three-dimensional time-of-flight sequence [J]. Magn Reson Imaging, 2017, 43: 129-135.
34
Lin ZY, Zhang XD, Guo L, et al. Clinical feasibility study of 3D intracranial magnetic resonance angiography using compressed sensing [J]. J Magn Reson Imaging, 2019, 50(6): 1843-1851.
35
Lu SS, Qi M, Zhang X, et al. Clinical evaluation of highly accelerated compressed sensing time-of-flight MR angiography for intracranial arterial stenosis [J]. AJNR Am J Neuroradiol, 2018, 39(10): 1833-1838.
36
Fujiwara Y, Muranaka Y. Improvement in visualization of carotid artery uniformity using silent magnetic resonance angiography [J]. Radiol Phys Technol, 2017, 10(1): 113-120.
37
Tanoue S, Uchiyama Y, Hirohata M, et al. Follow-up non-contrast MRA after treatment of intracranial aneurysms using microcoils with prominent metallic artifact: a comparative study of TOF-MRA and silent MRA [J]. Jpn J Radiol, 2020, 38(9): 853-859.
38
Ryu KH, Baek HJ, Moon JI, et al. Usefulness of noncontrast-enhanced silent magnetic resonance angiography (MRA) for treated intracranial aneurysm follow-up in comparison with time-of-flight MRA [J]. Neurosurgery, 2020, 87(2): 220-228.
39
Tomura N, Saginoya T, Kokubun M, et al. Comparison of time-of-flight-magnetic resonance angiography from silent scan magnetic resonance angiography in depiction of arteriovenous malformation of the brain [J]. J Comput Assist Tomogr, 2019, 43(6): 943-947.
40
Tomura N, Kokubun M, Horiuchi K, et al. Comparison of TOF-MRA and silent scan-MRA in depicting cerebral arteries in patients with Moyamoya disease [J]. Acta Radiol, 2019, 60(10): 1321-1328.
[1] 马晓菊, 梁潇, 段云友, 袁丽君, 赵萍. NBAV脂质纳泡对ApoE -/-小鼠动脉粥样硬化病变的评估和干预[J/OL]. 中华医学超声杂志(电子版), 2024, 21(06): 608-616.
[2] 赫兰, 杨泽堃, 张颖, 王玉东, 陈伟导, 王一同, 申锷. 双输入BCNN-ResNet模型对超声颈动脉斑块稳定性的分类诊断价值[J/OL]. 中华医学超声杂志(电子版), 2024, 21(02): 137-142.
[3] 吕琦, 惠品晶, 丁亚芳, 颜燕红. 颈动脉斑块易损性的超声造影评估及与缺血性卒中的相关性研究[J/OL]. 中华医学超声杂志(电子版), 2023, 20(10): 1040-1045.
[4] 张莲莲, 惠品晶, 丁亚芳. 颈部血管超声在粥样硬化斑块易损性评估中的应用价值[J/OL]. 中华医学超声杂志(电子版), 2023, 20(08): 816-821.
[5] 李强, 杨淼, 马龙, 尤晓涵, 张媛媛, 明霞光, 李春香, 武晓芳. 外周血miR-320b表达水平对颈动脉粥样硬化斑块性质的评价研究[J/OL]. 中华脑科疾病与康复杂志(电子版), 2022, 12(04): 234-240.
[6] 张家珺, 张海涛, 苏菲菲. 径向壁应变分析在冠心病诊疗中的应用[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 687-691.
[7] 冯佳佳, 刘丹, 张广炜, 金丽霞. microRNA与脑动脉粥样硬化斑块破裂的研究新进展[J/OL]. 中华临床医师杂志(电子版), 2022, 16(06): 601-604.
[8] 郭方明, 赵明俐, 颜凡辉, 刘萌萌, 王阳, 赵英杰, 刘远航, 张艳芬, 詹景冬. 光学相干断层成像在急性心肌梗死冠状动脉分层斑块病变中的应用[J/OL]. 中华诊断学电子杂志, 2024, 12(02): 73-79.
[9] 王林源, 熊鑫, 杨坤, 邓勇志. 基于冠状动脉CT血管成像的影像组学列线图鉴别诊断易损斑块的价值[J/OL]. 中华诊断学电子杂志, 2024, 12(01): 1-8.
[10] 熊鑫, 邓勇志. 基于血管内超声的机器学习在冠状动脉病变中的研究进展[J/OL]. 中华诊断学电子杂志, 2023, 11(03): 153-157.
[11] 刘英, 马利军, 王宝军, 刘晓林, 柴圣婷, 苏宁. 颅内动脉粥样硬化斑块成分及特征与缺血性脑卒中相关性的HRMR-VWI研究[J/OL]. 中华脑血管病杂志(电子版), 2023, 17(06): 549-556.
[12] 林雨, 王艳玲. 颈动脉斑块易损性的评估与干预的研究进展[J/OL]. 中华脑血管病杂志(电子版), 2023, 17(01): 66-69.
[13] 白艳, 董秋梅, 王雄耀. 颈动脉粥样硬化性缺血性卒中风险评估的研究进展[J/OL]. 中华脑血管病杂志(电子版), 2022, 16(06): 439-442.
[14] 朱欣伟, 李俊林, 张建平, 包金岗, 吴日乐. 颈动脉斑块内出血影像学检查的应用进展[J/OL]. 中华脑血管病杂志(电子版), 2022, 16(06): 427-431.
[15] 娄喆, 马春燕. 超声检查对颈动脉粥样硬化评估的研究进展[J/OL]. 中华脑血管病杂志(电子版), 2022, 16(03): 197-201.
阅读次数
全文


摘要