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Chinese Journal of Cerebrovascular Diseases(Electronic Edition) ›› 2021, Vol. 15 ›› Issue (04): 212-217. doi: 10.11817/j.issn.1673-9248.2021.04.003

• Expert Forum • Previous Articles     Next Articles

Advance in early recognition and magnetic resonance imaging diagnosis of cerebral small vessel disease

Hengheng Xu1, Yun Xu1,()   

  1. 1. Department of Neurology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China
  • Received:2020-12-13 Online:2021-08-09 Published:2021-09-10
  • Contact: Yun Xu

Abstract:

Cerebral small vessel disease (CSVD) refers to a series of pathological syndromes resulted from the pathophysiological changes in small arteries, perforating arteries and venules. Neuropathological studies of patients with CSVD have shown that inflammation and endothelial dysfunction play a key role in it, and further research in related fields would become an important means of understanding CSVD. In recent years, with the continuous improvement of MRI scanning intensity and the clinical development of new sequences, such as arterial spin-labeled perfusion imaging and diffusion tensor imaging, clinicians are able to evaluate smaller brain structures and lesions than ever before, so that the pathological features of CSVD can be identified at an very early stage before symptoms appear.

Key words: Cerebral small vessel disease, Magnetic resonance imaging, Identified, early

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