Neurovascular unit in cerebral small vessel disease: an update review

doi:10.11817/j.issn.1673-9248.2022.01.010

Abstract

Abstract:

Cerebral small vessel disease (CSVD) is a disorder of cerebral small vessels caused by various reasons, resulting in a series of clinical, imaging and pathological changes. Neurovascular unit is composed by neurons-glial cells-cerebral blood vessels. In recent year, with the deeper understanding of CSVD pathogenesis, there has been an increasing interest in the role of the interaction among different components of neurovascular unit. Thus, this review comprehensively elucidates the role of the interaction among its components in the pathogenesis of CSVD, so as to provide theoretical basis for the prevention and treatment.

Key words: Cerebral small vessel disease, Neurovascular unit, Pathogenesis

Jingshu Hong, Dengyang Han, Xiangyang Guo. Neurovascular unit in cerebral small vessel disease: an update review[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2022, 16(01): 48-52.

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