Research progress in diagnosis and treatment of cardiomyopathy-related ischemic stroke

doi:10.11817/j.issn.1673-9248.2022.05.013

Abstract

Abstract:

The cardiomyopathy can be divided into hypertrophic cardiomyopathy (familial, non-familial), dilated cardiomyopathy (familial, non-familial), restrictive cardiomyopathy (familial, non-familial), arrhythmogenic right ventricular cardiomyopathy, and unclassified cardiomyopathy (including left ventricular noncompaction and Takotsubo cardiomyopathy). For the cardiomyopathy-associated ischemic stroke patients, risk factors of stroke, treatment timing, and the course vary substantially. This article reviews the clinical characteristics, incidence, risk factors for embolism in various cardiomyopathies to guide the treatment of the related ischemic stroke.

Key words: Cardiomyopathy, Ischemic stroke, Embolism

Ying Li, Xueliang Qi, Liqun Feng, Tong Liu, Guangzhi Liu. Research progress in diagnosis and treatment of cardiomyopathy-related ischemic stroke[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2022, 16(05): 356-359.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhnxgbzz.cma-cmc.com.cn/EN/10.11817/j.issn.1673-9248.2022.05.013

https://zhnxgbzz.cma-cmc.com.cn/EN/Y2022/V16/I05/356

References 32

13	Wlodarska EK, Wozniak O, Konka M, et al. Thromboembolic complications in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy [J]. Europace, 2006, 8(8): 596-600.
14	Towbin JA, Lorts A, Jefferies JL. Left ventricular non-compaction cardiomyopathy [J]. Lancet, 2015, 386(9995): 813-825.
15	Yacoub HA, Sivakumar K, El-Hunjul M, et al. Ischemic stroke secondary to left ventricular noncompaction [J]. J Neurol Res, 2019, 9(4-5): 75-80.
16	Lee GH, Kim DK, Song YJ, et al. Stroke in a young individual with left ventricular noncompaction and left atrium standstill [J]. Korean Circ J, 2015, 45(5): 432-438.
17	Pöyhönen P, Kuusisto J, Järvinen V, et al. Left ventricular non-compaction as a potential source for cryptogenic ischemic stroke in the young: a case-control study [J]. PLoS One, 2020, 5(8): e0237228.
18	Aung N, Doimo S, Ricci F, et al. Prognostic significance of left ventricular noncompaction: systematic review and meta-analysis of observational studies [J]. Circ Cardiovasc Imaging, 2020, 13(1): e009712.
19	Y-Hassan S, Tornvall P. Epidemiology, pathogenesis, and management of takotsubo syndrome [J]. Clin Auton Res, 2018, 28(1): 53-65.
20	Kurisu S, Inoue I, Kawagoe T, et al. Incidence and treatment of left ventricular apical thrombosis in Takotsubo cardiomyopathy [J]. Int J Cardiol, 2011, 146(3): e58-e60.
21	Y-Hassan S, Holmin S, Abdula G, et al. Thrombo-embolic complications in takotsubo syndrome: review and demonstration of an illustrative case [J]. Clin Cardiol, 2019, 42(2): 312-319.
22	Tani T, Tanabe K, Ono M, et al. Left atrial volume and the risk of paroxysmal atrial fibrillation in patients with hypertrophic cardiomyopathy [J]. J Am Soc Echocardiogr, 2004, 17(6): 644-648.
23	Guttmann OP, Pavlou M, O'Mahony C, et al. Hypertrophic Cardiomyopathy Outcomes Investigators. Prediction of thrombo-embolic risk in patients with hypertrophic cardiomyopathy (HCM Risk-CVA) [J]. Eur J Heart Fail, 2015, 17(8): 837-845.
24	Kozdag G, Ciftci E, Vural A, et al. Silent cerebral infarction in patients with dilated cardiomyopathy: echocardiographic correlates [J]. Int J Cardiol, 2006, 107(3): 376-381.
25	Mandaliya R, Boigon M, Nweke N, et al. Left ventricular non-compaction syndrome misdiagnosed as dilated cardiomyopathy on several occasions, presenting with recurrent stroke [J]. Cardiol Res, 2014, 5(1): 42-47.
26	Matsuzono K, Ikeda Y, Deguchi S, et al. Cerebral embolic stroke after disappearing takotsubo cardiomyopathy [J]. J Stroke Cerebrovasc Dis, 2013, 22(8): e682-e683.
27	de Gregorio C. Cardioembolic outcomes in stress-related cardiomyopathy complicated by ventricular thrombus:a systematic review of 26 clinical studies [J]. Int J Cardiol, 2010, 141(1): 11-17.
28	Otani Y, Tokunaga K, Kawauchi S, et al. Cerebral infarction arising from takotsubo cardiomyopathy: case report and literature review [J]. NMC Case Rep J, 2016, 3(4): 119-123.
29	Santoro F, Stiermaier T, Tarantino N, et al. Left ventricular thrombi in takotsubo syndrome: incidence，predictors，and management: results from the GEIST (German Italian Stress Cardiomyopathy) registry [J]. J Am Heart Assoc, 2017, 6(12): e006990.
30	Jung H, Yang PS, Sung JH, et al. Hypertrophic cardiomyopathy in patients with atrial fibrillation: prevalence and associated stroke risks in a nationwide cohort study [J]. Thromb Haemost, 2019, 119(2): 285-293.
31	Dominguez F, Climent V, Zorio E, et al. Direct oral anticoagulants in patients with hypertrophic cardiomyopathy and atrial fibrillation [J]. Int J Cardiol, 2017, 248: 232-238.
32	Rujirachun P, Charoenngam N, Wattanachayakul P, et al. Efficacy and safety of direct oral anticoagulants (DOACs) versus vitamin K antagonist (VKA) among patients with atrial fibrillation and hypertrophic cardiomyopathy: a systematic review and meta-analysis [J]. Acta Cardiol, 2020, 75(8): 724-731.
1	Masarone D, Kaski JP, Pacileo G, et al. Epidemiology and clinical aspects of genetic cardiomyopathies [J]. Heart Fail Clin, 2018, 14(2): 119-128.
2	Ana CF, Joao PM, Daniela P, et al. Undetermined stroke genesis and hidden cardiomyopathies determined by cardiac magnetic resonance [J]. Neurology, 2020, 94(1): e107-e113.
3	中华医学会心血管病学分会中国成人肥厚性心肌病诊断与治疗指南编写组, 中华心血管病杂志编辑委员会. 中国成人肥厚型心肌病诊断与治疗指南 [J]. 中华心血管病杂志, 2017, 45(12): 1015-1032.
4	Falasconi G, Pannone L, Slavich M, et al. Atrial fibrillation in hypertrophic cardiomyopathy: pathophysiology, diagnosis and management [J]. Am J Cardiovasc Dis, 2020, 10(4): 409-418.
5	Haruki S, Minami Y, Hagiwara N. Stroke and embolic events in hypertrophic cardiomyopathy: risk stratification in patients without atrial fibrillation [J]. Stroke, 2016, 47(4): 936-942.
6	Gottdiener JS, Gay JA, VanVoorhees L, et al. Frequency and embolic potential of left ventricular thrombus in dilated cardiomyopathy: assessment by 2-dimensional echocardiography [J]. Am J Cardiol, 1983, 52(10): 1281-1285.
7	Sharma ND, McCullough PA, Philbin EF, et al. Left ventricular thrombus and subsequent thromboembolism in patients with severe systolic dysfunction [J]. Chest, 2000, 117(2): 314-320.
8	Feng D, Edwards WD, Oh JK, et al. Intracardiac thrombosis and embolism in patients with cardiac amyloidosis [J]. Circulation, 2007, 116(21): 2420-2426.
9	Zubkov AY, Rabinstein AA, Dispenzieri A, et al. Primary systemic amyloidosis with ischemic stroke as a presenting complication [J]. Neurology, 2007, 69(11): 1136-1141.
10	Ammash NM, Seward JB, Bailey KR, et al. Clinical profile and outcome of idiopathic restrictive cardiomyopathy [J]. Circulation, 2000, 101(21): 2490-2496.
11	Sayed A, Pal S, Poplawska M, et al. Arrhythmogenic right ventricular cardiomyopathy diagnosis [J]. Cardiol Rev, 2020, 28(6): 319-324.
12	Hamilton-Craig C, McGavigan A, Semsarian C, et al. The Cardiac Society of Australia and New Zealand Position Statement on the diagnosis and management of arrhythmogenic right ventricular cardiomyopathy (2019 Update) [J]. Heart Lung Circ, 2020, 29(1): 40-48.

[1]	Dandan Chen, Xiaojing Ma, Juan Xia. Evaluation of right ventricular function in patients with hypertrophic cardiomyopathy by two-dimensional speckle tracking imaging [J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2023, 20(04): 417-423.
[2]	Cheng Zhang, Haijun He, Guangyi Zhang, Binglang Xiong, Tianzhao Tian, Shiyi Sun, Zixuan Wu. Meta-analysis anticoagulant prevention of thrombosis after knee arthroscopy [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(03): 340-347.
[3]	Yu Chen, Fang Feng, Lu Zhang, Jian Liu. Bioinformatics analysis to screen key pathogenic genes in septic cardiomyopathy [J]. Chinese Journal of Critical Care Medicine(Electronic Edition), 2023, 16(04): 286-291.
[4]	Jie Zhang, Ming Xie. Prevention and treatment of perioperative venous thromboembolism in patients with inguinal hernia [J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2023, 17(04): 394-399.
[5]	Huijuan Shang, Xiaodong Yuan. Improvement of prognosis of acute cerebral ischemic stroke with edaravone dexkanol after mechanical thrombectomy [J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2023, 09(05): 295-301.
[6]	Kechun Chen, Qiuyi Wu, Jian Li, Yin Zhou, Zhou Xu. Relationship between the first CT signs after mechanical thrombectomy and prognosis of patients based on different neutrophil-lymphocyte ratios [J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2023, 13(04): 215-221.
[7]	Xiangning Ren, Xiaoming Zheng. Research progress of ischemic stroke and peripheral immune response [J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2023, 13(03): 175-179.
[8]	Shoufa Zhao, Shu Wang, Larissa Miare Vados, Alberto Cantidio Ferreira. Observation on the efficacy of Xingnao Kaiqiao acupuncture combined with rehabilitation therapy in the treatment of ischemic stroke in the recorvery period [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(04): 151-155.
[9]	Xuping Zhang, Jiacheng Liu, Ge Zhang, Yanjiao Du, Shao Li, Dandan Shang, Hao Wang, Yan Li, Zhihui Duan. CYP2C19 gene polymorphism combined with thromboelastogram-guided antiplatelet therapy for patients with the large artery atherosclerosis and non-disabling ischemic cerebrovascular events (NICE) [J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(05): 477-481.
[10]	Zeping Jin, Jing Dong, Yunpeng Liu, Yang Wang. Correlation between microbiota-gut-brain axis and the risk factors of ischemic stroke [J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(05): 510-517.
[11]	Chenjun Yin, Zhe Zhang, Xiaoming Li. Advance in mechanisms of patent foramen ovale-associated thrombosis [J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(04): 307-311.
[12]	Xin Li, Yongkai Li, Shuqing Jiang, Xarbatgul·Samat, Jianzhong Yang. Risk factors related to hemorrhage transformation after intravenous thrombolysis in acute ischemic stroke [J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(04): 331-336.
[13]	Ying Deng, Shan Huang, Huixiu Hu, Chao Sun. Prevalence of risk factors in aged patients with ischemic stroke [J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(04): 344-349.
[14]	Xingyun Yuan, Wanhong Chen, Liping Yu, Li Yao. Interventional treatment of vertebral artery occlusion with Wallenberg syndrome [J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(04): 394-399.
[15]	Lingzhi Qiu, Ping Hu, Ting Luo, Hua Yan. Research progress of the relationship between lipoprotein(a) and atrial fibrillation [J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(03): 280-284.

Please choose a citation manager

Content to export