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Chinese Journal of Cerebrovascular Diseases(Electronic Edition) ›› 2025, Vol. 19 ›› Issue (03): 250-254. doi: 10.3877/cma.j.issn.1673-9248.2025.03.012

Special Issue:

• Review • Previous Articles     Next Articles

Research advances in the clinical applications of intrasaccular flow disruptors

Xiaowen Zhang1, Hailong Zhong2, Xin Tong2, Mengyan Fan1, Jiaxin Wan1, Rijin Lin1, Jing Li1, Sheng Guan,1()   

  1. 1 Neurointerventional Department, the first affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China
    2 Cerebrovascular Disease Department, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
  • Received:2024-08-21 Online:2025-06-01 Published:2025-08-11
  • Contact: Sheng Guan

Abstract:

Over recent decades, significant advancements have been achieved in endovascular treatment techniques for intracranial aneurysms, alongside the continuous emergence of novel endovascular devices. Among these, intrasaccular flow disruptors represent a relatively new class of devices developed in recent years. These devices bears a strong resemblance to flow-diverting stents and are primarily employed for treating vascular abnormalities such as cerebral aneurysms and arteriovenous malformations (AVMs). Currently, mainstream intrasaccular flow disruptors include the Woven EndoBridge (WEB) device, the Luna Aneurysm Embolization System, the Medina Embolic Device, the Contour Neurovascular System, and the Neqstent Coil-Assisted Flow Diverter. Research on intrasaccular flow disruptors has already been extensively conducted internationally, with their safety and efficacy preliminarily established. However, domestic research in this area remains limited. This significant research gap underscores the necessity and urgency of conducting studies on intrasaccular flow disruptors within China. Therefore, this review aims to provide a comprehensive retrospective analysis and summary of existing flow disruptors and related treatment experiences, with the goal of bridging the domestic research gap in this field.

Key words: Intracranial aneurysms, Endovascular treatment, Intrasaccular flow disruptors

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