Post-stroke delirium (PSD) is one of the most common complications of stroke, imposing a heavy burden on patients, families, healthcare providers, and society. Non-pharmacological interventions, which focus on identifying risk factors and implementing individualized management strategies, play a pivotal role in the prevention and treatment of PSD. This article focused on the risk factors of PSD and corresponding non-pharmacological intervention methods, systematically organizing multiple management strategies. It aimed to provide scientific and comprehensive non-pharmacological intervention schemes for patients with PSD and high-risk groups, improve the rehabilitation and quality of life of patients, so as to effectively achieve the prevention and treatment goals of this disease.