Research progress of patent foramen ovale and cryptogenic stroke

doi:10.3877/cma.j.issn.1673-9248.2026.05.014

Abstract

Abstract:

In recent years, the correlation between patent foramen ovale (PFO) and stroke has attracted much attention from neurologists and cardiologists, especially in young patients with cryptogenic stroke, in whom PFO screening has become mandatory. For this purpose, this article reviews the formation of the foramen ovale, the incidence of PFO, the methods of PFO detection, the imaging characteristics of PFO-related stroke, and the treatment of PFO-related stroke. The aim is to enhance awareness of the correlation between cryptogenic stroke and PFO.

Key words: Patent foramen ovale, Cryptogenic stroke, Imaging characteristics, Patent foramen ovale closure, Medical therapy

Ke Jia, Zhongyao Zhang, Heng Chi, Xiaobing Li, Xiaomei Tang. Research progress of patent foramen ovale and cryptogenic stroke[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2026, 20(05): 579-584.

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