Application and prospect of Butylphthalide in the treatment of cognitive impairment

doi:10.11817/j.issn.1673-9248.2024.01.004

Abstract

Abstract:

Cognitive impairment is a severe and advanced neurological detrimental syndrome that imposes a substantial burden on families and society. Few drugs can treat cognitive impairment, and their efficacy is limited. It is urgent to seek new treatment strategies. In recent years, studies have shown that dl-3-n-Butylphthalide can be used to treat cognitive impairment, while its efficacy and safety still need to be reinforced by more evidence. This review summarizes the pharmacological mechanism, basic researches and clinical studies of dl-3-n-Butylphthalide in cognitive disorders. This paper may provide a new option for treating cognitive conditions.

Key words: Vascular cognitive impairment, Alzheimer's disease, dl-3-n-Butylphthalide, Pharmacological mechanism, Drug therapy

Xiaoxiao Zhao, Jiating Qiu, Yishu Zhang, Rong Zhang, Peng Zhang, Xiaolei Liu. Application and prospect of Butylphthalide in the treatment of cognitive impairment[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2024, 18(01): 19-26.

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