Effects of cognitive-motor dual-task training on post-stroke cognitive impairment

doi:10.3877/cma.j.issn.1673-9248.2025.02.002

Abstract

Abstract:

Objective

To investigate the effects of cognitive-motor dual-task training (DTT)on multidimensional cognitive function and activities of daily living (ADL) in patients with post-stroke cognitive impairment (PSCI).

Methods

A total of 28 eligible patients with PSCI admitted to the Department of Rehabilitation Medicine at Beijing Tiantan Hospital, Capital Medical University, from August 2023 to September 2024 were enrolled and randomly assigned to a control group (n=14) and an intervention group (n=14).The control group received cognitive training alone (5 sessions/week, 30 minutes/session, for 2 weeks),while the intervention group underwent cognitive-motor DTT with identical training frequency and duration.Pre- and post-training scores on the Stroop color-word test (SCWT), Rey-Osterrieth complex figure test (ROCF),digit symbol substitution test (DSST), and Alzheimer's disease assessment scale-cognitive subscale (ADAS-Cog)were compared between groups.Additionally, differences in Montreal cognitive assessment (MoCA),modified Barthel index (MBI), and functional independence measure (FIM) scores at 1-month follow-up were analyzed relative to baseline.

Results

Compared with the control group, the intervention group showed significantly higher scores in DSST (P＜0.05), MBI (P＜0.05), and FIM (P＜0.05), and lower ADAS-Cog scores (P＜0.05) at 1-month follow-up.Both groups exhibited improved ROCF and MoCA scores after training, without statistical significance.SCWT completion time decreased post-training, without statistical significance (P＞0.05).

Conclusion

Cognitive-motor DTT may cognitive functions related to attention and memory, as well as improve ADL capabilities in PSCI patients.Further research is needed to validate its long-term efficacy.

Key words: Dual-task training, Post-stroke cognitive impairment, Rehabilitation

Runyi Du, Yumei Zhang, Lipeng Liu, Weijun Gong. Effects of cognitive-motor dual-task training on post-stroke cognitive impairment[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2025, 19(02): 87-93.

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Figures/Tables 2

基础资料	对照组（14 例）	观察组（14 例）	统计值	P值
年龄（岁， $\overset{ˉ}{x}$ ± s ）	68.00±6.78	70.21±7.08	t=0.845	0.406
性别[ 例（%）]			χ ²=0.622	0.693
男	10（71.4）	8（57.1）
女	4（28.6）	6（42.9）
既往史[ 例（%）]
高血压	13（92.9）	10（71.4）	χ ²=2.191	0.139
糖尿病	8（57.1）	9（64.3）	χ ²=0.150	0.699
高脂血症	3（21.4）	7（50）	χ ²=2.489	0.237
冠心病	5（35.7）	2（14.3）	χ ²=1.714	0.383
卒中半球[ 例（%）]			χ ²=2.333	0.127
左侧	4（28.6）	8（57.1）
右侧	10（71.4）	6（42.9）
发病时间（月， $\overset{ˉ}{x}$ ± s ）	0.82±0.80	0.92±0.76	t=0.341	0.736

基础资料	对照组（14 例）	观察组（14 例）	统计值	P值
年龄（岁， $\overset{ˉ}{x}$ ± s ）	68.00±6.78	70.21±7.08	t=0.845	0.406
性别[ 例（%）]			χ ²=0.622	0.693
男	10（71.4）	8（57.1）
女	4（28.6）	6（42.9）
既往史[ 例（%）]
高血压	13（92.9）	10（71.4）	χ ²=2.191	0.139
糖尿病	8（57.1）	9（64.3）	χ ²=0.150	0.699
高脂血症	3（21.4）	7（50）	χ ²=2.489	0.237
冠心病	5（35.7）	2（14.3）	χ ²=1.714	0.383
卒中半球[ 例（%）]			χ ²=2.333	0.127
左侧	4（28.6）	8（57.1）
右侧	10（71.4）	6（42.9）
发病时间（月， $\overset{ˉ}{x}$ ± s ）	0.82±0.80	0.92±0.76	t=0.341	0.736

量表	对照组（14 例）				观察组（14 例）				t值^*	P值^*
量表	训练前	训练后	t值	P值	训练前	训练后	t值	P值	t值^*	P值^*
认知功能量表
MoCA（分）	20.36±2.37	20.91±2.75	1.473	1.165	18.50±4.57	20.07±3.99	1.973	0.070	1.153	0.264
SCWT 完成时间（s）	139.86±105.34	126.66±83.05	0.912	0.378	138.44±78.84	120.14±68.95	2.019	0.065	0.561	0.580
ROCF（分）	15.96±10.40	18.50±10.27	2.645	0.020	16.694±10.59	23.00±9.23	3.825	0.002	1.896	0.069
DSST（分）	16.00±7.35	17.42±7.86	1.652	0.123	12.32±6.86	17.42±7.50	6.543	0.000	2.979	0.006
ADAS-Cog（分）	15.64±3.88	14.43±3.84	2.518	0.026	19.21±6.74	16.21±6.83	5.408	0.000	2.163	0.040
日常生活能力量表
MBI（分）	84.64±12.48	83.80±12.93	0.770	0.455	81.07±13.33	84.29±12.84	2.090	0.057	2.148	0.041
FIM（分）	106.14±11.97	106.14±12.00	＜0.999	1.000	103.36±12.13	106.50±11.23	2.914	0.012	2.176	0.039

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