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中华脑血管病杂志(电子版) ›› 2024, Vol. 18 ›› Issue (02) : 115 -120. doi: 10.11817/j.issn.1673-9248.2024.02.004

临床研究

非优势供血侧眶上锁孔入路显微手术治疗破裂前交通动脉瘤的临床疗效
杨德红1, 万宇晖1, 杨凯1, 陈爱林1, 戴纯刚1, 陈延明1, 陈炳霖1, 朱卿1,()   
  1. 1. 215004 江苏 苏州,苏州大学附属第二医院神经外科
  • 收稿日期:2023-11-05 出版日期:2024-04-01
  • 通信作者: 朱卿
  • 基金资助:
    苏州市科技发展计划项目(SYS2019067); 苏州大学附属第二医院科研预研基金项目(SDFEYBS2217)

Clinical effect of microsurgical clipping via supraorbital keyhole approach of non-dominant feeder for ruptured anterior communicating artery aneurysm

Dehong Yang1, Yuhui Wan1, Kai Yang1, Ailin Chen1, Chungang Dai1, Yanming Chen1, Binglin Chen1, Qing Zhu1,()   

  1. 1. Department of Neurosurgery, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China
  • Received:2023-11-05 Published:2024-04-01
  • Corresponding author: Qing Zhu
引用本文:

杨德红, 万宇晖, 杨凯, 陈爱林, 戴纯刚, 陈延明, 陈炳霖, 朱卿. 非优势供血侧眶上锁孔入路显微手术治疗破裂前交通动脉瘤的临床疗效[J]. 中华脑血管病杂志(电子版), 2024, 18(02): 115-120.

Dehong Yang, Yuhui Wan, Kai Yang, Ailin Chen, Chungang Dai, Yanming Chen, Binglin Chen, Qing Zhu. Clinical effect of microsurgical clipping via supraorbital keyhole approach of non-dominant feeder for ruptured anterior communicating artery aneurysm[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2024, 18(02): 115-120.

目的

探讨非优势供血侧眶上锁孔入路显微手术治疗破裂前交通动脉瘤的临床疗效。

方法

回顾性分析苏州大学附属第二医院2016年1月至2020年10月69例接受眶上锁孔入路显微手术治疗的破裂前交通动脉瘤患者的临床资料,其中经非优势供血侧入路32例,经优势供血侧入路37例。采用单因素分析比较2组病例的手术时间、术中动脉瘤破裂率、术中动脉瘤夹使用个数、是否切除额叶直回、动脉瘤夹闭不全率、前交通动脉瘤复合体变异扭转率及预后情况的差异。

结果

非优势供血侧入路组与优势供血侧入路组的手术时间分别为(190±61)min和(204±55)min,术中发生动脉瘤破裂分别有9例(24.3%)和4例(12.5%),术中动脉瘤夹使用个数分别为(1.38±0.61)个和(1.35±0.63)个,额叶直回切除率分别为37.5%(12/32)和48.6%(18/37),动脉瘤夹闭不全率分别为3.1%(1/32)和2.7%(1/37),前交通动脉瘤复合体变异扭转率分别为50.0%(16/32)和37.8%(14/37),出院时预后良好率分别为78.1%(25/32)和75.7%(28/37),出院后1个月、3个月、6个月、12个月的预后良好率均分别为78.1%(25/32)和73.0%(27/37),差异均无统计学意义(P均>0.05)。

结论

经非优势供血侧眶上锁孔入路显微手术治疗破裂前交通动脉瘤安全、有效。

Objective

To explore the clinical effect of microsurgical clipping via supraorbital keyhole approach of non-dominant feeder for ruptured anterior communicating artery aneurysms.

Methods

The clinical data of 69 patients with ruptured anterior communicating artery aneurysm who underwent microsurgery with supprorbital keyhole approach in the Second Affiliated Hospital of Soochow University from January 2016 to October 2020 were retrospectively analyzed. Among them, 32 patients underwent non-dominant feeder approach and 37 patients underwent dominant feeder approach. The operation duration, the rate of intraoperative aneurysm rupture, the number of intraoperative aneurysm clips, the resection rate of frontal gyrus, the rate of incomplete aneurysm clipping, the variation and torsion rates of anterior communicating artery aneurysm complex, and the good prognosis rate were compared between the two groups.

Results

The operative time of the non-dominant feeder approach group and the dominant feeder approach group was (190±61) min and (204±55) min, respectively. Intraoperative aneurysm rupture occurred in 9 cases (24.3%) and 4 cases (12.5%) in the two groups, respectively. The number of intraoperative aneurysm clips were (1.38±0.61) and (1.35±0.63), the resection rate of frontal gyrus were 37.5% (12/32) and 48.6% (18/37), the rate of aneurysm occlusion was 3.1% (1/32) and 2.7% (1/37), and the variation and torsion rates of anterior communicating artery aneurysm complex were 16 cases (50.0%) and 14 cases (37.8%), respectively. The good prognosis rate of the two groups at discharge were 25 (78.1%) and 28 (75.7%), respectively, and the good prognosis rate at 1 month, 3 months, 6 months and 12 months after discharge were 25 (78.1%) and 27 (73.0%), respectively, with no statistical significance (all P>0.05).

Conclusion

Microsurgery through the supraorbital keyhole approach on the non-dominant feeder is safe and effective for the treatment of ruptured anterior communicating artery aneurysm.

图1 患者头皮切口图片。图a患者头皮切口侧面图;图b患者头皮切口俯视图。颅骨钻孔、骨窗、颧弓、颞肌附着缘已一并标出
图2 非优势供血侧眶上锁孔入路夹闭破裂前交通动脉(ACoA)动脉瘤病例图。患者女性,53岁,因“突发头痛8 h伴呕吐”急诊入院。图a急诊头部CT示鞍上池、左侧侧裂池、环池蛛网膜下腔出血。图b急诊CT血管成像示ACoA动脉瘤,指向上方,ACoA复合体扭转变异明显,左侧A1段为优势供血侧,右侧为非优势供血侧(俯视图)。图c手术中动脉瘤夹闭前图片。图d动脉瘤夹闭后图片。图e术后复查数字减影血管造影显示动脉瘤夹闭完全。图f骨质三维重建显示右侧眶上锁孔入路骨窗
表1 2组单发性破裂前交通动脉动脉瘤患者的一般临床资料比较
表2 2组单发性破裂前交通动脉动脉瘤患者的手术及预后资料比较
表3 2组单发性破裂前交通动脉动脉瘤患者预后良好情况比较[例(%)]
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