分析急性重症颅内静脉窦血栓患者血管内介入治疗的安全性及有效性。

收集2024年2月1日至6月1日在空军军医大学第一附属医院治疗的3例确诊为急性重症颅内静脉窦血栓并行血管内介入治疗患者的临床资料，回顾性分析其临床表现、影像学特征、手术方式和器械、药物治疗方案及随访结果并复习相关文献。

在3例患者中，女性2例（1例为孕早期、1例为产褥期发病），男性1例。3例患者临床表现均有颅高压和偏瘫，其中，1例有意识障碍，2例有癫痫性发作。3例患者头颅影像学显示：均有静脉性脑梗死，均累及上矢状窦及双侧横窦，其中2例伴出血转化。3例患者均选用Solitaire（6 mm×30 mm）取栓支架联合中间导管取栓，均取得部分再通，术后留置导管接触性静脉溶栓并取得满意效果，临床症状迅速好转。

急性重症颅内静脉窦血栓患者血管内介入治疗是安全有效的。

To evaluate the safety and efficacy of endovascular treatment for patients with acute severe cerebral venous sinus thrombosis.

Clinical data were collected from 3 patients diagnosed with acute severe cerebral venous sinus thrombosis who underwent with endovascular treatment at the First Affiliated Hospital, Air Force Medical University from February 1 to June 1, 2024. A retrospective analysis was conducted on their clinical manifestations, imaging characteristics, surgical techniques and devices used, medication regimens, and follow-up outcomes, supplemented by a review of relevant literature.

The cohort consisted of two female patients (one in early pregnancy and one postpartum) and one male patient. All three exhibited clinical manifestations of intracranial hypertension and hemiplegia, with one case showing conscious disturbance and two experiencing epileptic seizures. Cranial imaging revealed venous cerebral infarction in all patients, involving the superior sagittal sinus and bilateral transverse sinuses, with two cases showing hemorrhagic transformation. All patients underwent thrombectomy using Solitaire (6 mm×30 mm) stents-retriever combined with intermediate catheter retrieval technique, achieving partial recanalization. Subsequent catheter-directed intravenous thrombolysis resulted in satisfactory recanalization outcomes and rapid clinical improvement.

Endovascular treatment demonstrates both safety and efficacy in the management of acute severe cerebral venous sinus thrombosis.