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中华脑血管病杂志(电子版) ›› 2026, Vol. 20 ›› Issue (05) : 473 -484. doi: 10.3877/cma.j.issn.1673-9248.2026.05.001

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脑出血的立体化功能康复:从临床现状到系统管理
王凯文1, 冯嘤鹤2, 刘清源2, 王硕2,†()   
  1. 1 100050 北京,首都医科大学附属北京友谊医院神经外科
    2 100070 北京,首都医科大学附属北京天坛医院神经外科
  • 收稿日期:2026-06-02 出版日期:2026-10-01
  • 通信作者: 王硕
  • 基金资助:
    国家科技重大专项(2026ZD0554503)

Multidimensional functional rehabilitation for intracerebral hemorrhage: current clinical practice and systematic management

Kaiwen Wang1, Yinghe Feng2, Qingyuan Liu2, Shuo Wang2,†()   

  1. 1 Department of Neurosurgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
    2 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
  • Received:2026-06-02 Published:2026-10-01
  • Corresponding author: Shuo Wang
引用本文:

王凯文, 冯嘤鹤, 刘清源, 王硕. 脑出血的立体化功能康复:从临床现状到系统管理[J/OL]. 中华脑血管病杂志(电子版), 2026, 20(05): 473-484.

Kaiwen Wang, Yinghe Feng, Qingyuan Liu, Shuo Wang. Multidimensional functional rehabilitation for intracerebral hemorrhage: current clinical practice and systematic management[J/OL]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2026, 20(05): 473-484.

脑出血患者经急性期救治存活后,70%以上的患者仍存在意识、运动、认知、言语或吞咽等功能障碍。急性期救治后,康复治疗的临床实施仍面临启动时机不统一、评估标准不一致、院内外衔接不畅、康复资源差异大等问题,进而影响患者的长期功能恢复。脑出血康复不应仅局限于出院后短期训练,而应该从多方面、多层次对患者的各个功能障碍进行评价,在急性期、亚急性期和慢性期之间保持连续的管理。临床治疗决策要以高质量的循证证据为依据,联合多学科团队,创建医院-康复中心-社区-居家一体化体系,防止患者出院后康复治疗断层。神经调控技术可以作为传统康复的补充手段,但是其适用人群、启动时机、安全边界还需要根据血肿吸收情况、术后状态、癫痫风险、生命体征稳定性进行综合判断。本文以2019—2025年脑出血康复相关随机对照试验、系统综述、临床指南为依据,对急性期后功能恢复、神经调控干预、连续康复管理的研究进展进行梳理,归纳为立体化功能康复。鉴于现有证据多来源于缺血性脑卒中或混合脑卒中人群,立体化功能康复对脑出血患者的临床疗效仍需更多前瞻性研究验证。

More than 70% of patients who survive the acute phase of intracerebral hemorrhage continue to experience impairments in consciousness, motor function, cognition, speech, or swallowing. Following acute treatment, rehabilitation practice is often affected by inconsistent timing of initiation, non-uniform assessment standards, poor coordination between inpatient and post-discharge care, and regional disparities in rehabilitation resources, all of which may hinder long-term functional recovery. Rehabilitation for intracerebral hemorrhage should not be limited solely to short-term training following hospital discharge; instead, patients' functional impairments should be assessed from multiple perspectives, with continuous management throughout the acute, subacute, and chronic phases. Clinical decisions should be based on high-quality evidence, supported by multidisciplinary teamwork, and care should be delivered through an integrated system linking hospitals, rehabilitation centers, communities, and patients' homes, so as to avoid interruptions in rehabilitation after discharge. Neuromodulation may serve as an adjunct to conventional rehabilitation, but patient selection, timing of initiation, and safety limits should be determined according to hematoma resolution, postoperative status, seizure risk, and the stability of vital signs. Based on randomized controlled trials, systematic reviews, and clinical guidelines on rehabilitation after intracerebral hemorrhage published between 2019 and 2025, this article reviews advances in post-acute functional recovery, neuromodulation, and continuous rehabilitation management and integrates them into a multidimensional functional rehabilitation approach. Since most of the available evidence comes from patients with ischemic stroke or mixed stroke populations, further prospective studies are needed to determine the effectiveness of this approach specifically in patients with intracerebral hemorrhage

表1 脑出血微创外科手术主要临床试验对比
图1 立体化功能康复的CHP原则框架图 注:C为全面性,覆盖功能障碍的多维度(意识、运动、认知、言语、吞咽、心理)、疾病全周期(超急性期至慢性期)、患者多层次需求(医疗、康复、营养、心理、社会支持);H为高级别证据,基于严格的方法学和数据库建设;P为持久性,强调长时程、动态、连续性管理;MDT为多学科团队;RCT为随机对照试验;GRADE为推荐意见分级、评估、制定和评价。CHP原则是本文提出的一种立体化功能康复核心理念
表2 从传统康复到立体化功能康复的5个范式转变
表3 神经调控技术在脑出血康复中的应用对比
图2 神经调控技术时序选择决策树 注:GCS为格拉斯哥昏迷评分;CRS-R为昏迷恢复量表修订版;FMA-UE为上肢Fugl-Meyer评分;MMSE为简易精神状态检查量表;MoCA为蒙特利尔认知评估量表;taVNS为经皮耳迷走神经刺激;tDCS为经颅直流电刺激;CIMT为约束诱导运动疗法;rTMS为重复经颅磁刺激;VNS为迷走神经刺激;MCS为最小意识状态;DBS为脑深部电刺激;PET为正电子发射断层显像;fMRI为功能磁共振成像;EEG为脑电图
图3 医院-康复中心-社区-居家三级闭环管理体系流程图 注:taVNS为经皮耳迷走神经刺激;tDCS为经颅直流电刺激;MDT为多学科团队;PT为物理治疗师;OT为作业治疗师;ST为言语治疗师;TMS为经颅磁刺激;VNS为迷走神经刺激;DBS为脑深部电刺激;AI为人工智能
表4 脑出血患者功能障碍患病率、主要表现及康复特点
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