With the advancement of new technology and the guidance of national health administration, great progress has been made in the area of stroke care in recent years. However, a great deal of problems remain in the stroke health care system in China. The medical resources and technologies across China present huge difference, and few patients could arrive the hospital capable of stroke management within the narrow time window. The high disability and recurrence rate brought about by stroke remains to be the main challenge in the present time. This article will give a brief review of the key advances in stroke diagnosis and therapy, and a general introduction about the application of artificial intelligence in acute stroke management. In addition, some implications or prospects were also proposed here.