Association between adverse drug reactions by cerebrovascular drugs and the gender, age of patients

doi:10.3877/cma.j.issn.1673-9248.2014.02.005

Abstract

Abstract:

Objective

To investigate the use of adverse reactions in patients with cerebrovascular drugs occurred gender and age relationship.

Methods

Using cerebrovascular drugs in our hospital from March 2012 to March 2014 after the adverse reactions in patients selected 200 patients were analyzed retrospectively, including 128 cases of male (64%), 72 cases were female (36%). 60 years of age or older in 117 patients (58.50%), < 60 years old in 83 patients (41.50%), the data analysis on the adverse reaction.

Results

The occurrence rate of adverse reactions of male patients was higher than that of control group, with significant difference (P < 0.05), different ages of patients with adverse reactions of different, 50~59 years old and 60~69 years old age in two patients occurred adverse reaction rate are the highest, with significant difference (P < 0.05).

Conclusions

Cerebrovascular drugs can cause a lot of adverse reactions, and adverse reaction occurred in the age and gender of patients have a greater relationship.

Key words: Cerebral vascular disease, Drug therapy, Adverse reaction

Guangxing Yue. Association between adverse drug reactions by cerebrovascular drugs and the gender, age of patients[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2014, 08(02): 15-17.

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Figures/Tables 2

References 15

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组别	例数	皮疹	头晕	咳嗽	头痛	呕吐	过敏样反应
男性组	128	44(34.38)	38(29.69)	29(22.66)	19(14.84)	20(27.78)	17(13.28)
女性组	72	15(20.83)	12(16.67)	10(13.89)	4(5.56)	9(12.50)	10(13.89)
χ2	?	4.1945	4.0138	3.8912	3.8567	4.3816	0.3781
P	?	0.0376	0.0397	0.0421	0.0456	0.0342	0.7829

组别	例数	皮疹	头晕	咳嗽	头痛	呕吐	过敏样反应
男性组	128	44(34.38)	38(29.69)	29(22.66)	19(14.84)	20(27.78)	17(13.28)
女性组	72	15(20.83)	12(16.67)	10(13.89)	4(5.56)	9(12.50)	10(13.89)
χ2	?	4.1945	4.0138	3.8912	3.8567	4.3816	0.3781
P	?	0.0376	0.0397	0.0421	0.0456	0.0342	0.7829

组别	例数	皮疹	头晕	咳嗽	头痛	呕吐	过敏样反应
>80	19	3(15.79)	4(21.05)	6(31.58)	3(15.79)	2(10.53)	2(10.53)
70～80	30	11(36.67)	14(46.67)	15(50.00)	10(33.33)	8(26.67)	6(20.00)
60～69	68	34(50.00)	36(52.94)	37(54.41)	25(36.76)	21(30.88)	18(26.47)
50～59	48	29(60.42)	30(62.50)	19(39.58)	18(37.50)	16(33.33)	14(29.17)
40～49	25	9(36.00)	8(32.00)	8(16.67)	7(14.58)	5(10.42)	5(10.42)
<40	10	1(10.00)	2(20.00)	2(20.00)	3(30.00)	1(10.00)	1(10.00)

组别	例数	皮疹	头晕	咳嗽	头痛	呕吐	过敏样反应
>80	19	3(15.79)	4(21.05)	6(31.58)	3(15.79)	2(10.53)	2(10.53)
70～80	30	11(36.67)	14(46.67)	15(50.00)	10(33.33)	8(26.67)	6(20.00)
60～69	68	34(50.00)	36(52.94)	37(54.41)	25(36.76)	21(30.88)	18(26.47)
50～59	48	29(60.42)	30(62.50)	19(39.58)	18(37.50)	16(33.33)	14(29.17)
40～49	25	9(36.00)	8(32.00)	8(16.67)	7(14.58)	5(10.42)	5(10.42)
<40	10	1(10.00)	2(20.00)	2(20.00)	3(30.00)	1(10.00)	1(10.00)

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