The research progress in clinical characteristics and imaging of subjective cognitive decline

doi:10.11817/j.issn.1673-9248.2020.05.002

Abstract

Abstract:

Subjective cognitive decline (SCD) is a state in which an individual complains of a decline in cognitive function compared with the previous, while there is no objective evidence of neuropsychological abnormalities. Numerous evidences indicate that SCD may be the earliest symptom in Alzheimer's disease (AD) spectrum. At the same time, SCD presents a strong heterogeneity. How to identify progressive SCD patients in order to achieve ultra-early prevention and intervention of AD is of difficulty in the current research. This review presents SCD-related information in terms of research criteria, cognitive progress factors, marker research status, current research limitations, and future research directions.

Key words: Subjective cognitive decline, Cognitive impairment, Imaging biomarkers

Caimei Luo, Yun Xu. The research progress in clinical characteristics and imaging of subjective cognitive decline[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2020, 14(05): 259-263.

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