Abstract:

Magnetic resonance imaging is the preferred imaging examination method for the diagnosis of cerebral small vessel disease. Its main manifestations include recent small subcortical infarct, lacune (of presumed vascular origin), white matter hyperintensity (of presumed vascular origin) , perivascular space, cerebral microbleed, cortical superficial siderosis, brain atrophy, and cortical cerebral microinfarct. The above imaging manifestations often occur simultaneously or successively. In recent years, researchers have proposed a "total small vessel diseases score", that is, combining different magnetic resonance imaging markers of small cerebral vascular diseases into a measurement index, which is more accurate capture of all brain injuries from cerebrovascular diseases through the assessment of total burden of imaging markers. Movement dysfunction are the main clinical burden for patients with cerebrovascular diseases in the later stage. Research on cerebrovascular imaging markers and movement disorders has received great attention. This study aims to provide an overview of the mechanism of movement disorders in cerebral small vessel disease, the association between various imaging markers and movement disorders, and emerging imaging evaluation methods. It is desirable for researchers and clinical physicians will have an understanding of the relationship between cerebrovascular imaging markers and movement disorders, which will be beneficial for future clinical and scientific research work.

Key words: Cerebral small vessel disease, Neuroimaging, Motor dysfunction, Total small vessel diseases score