Research progress of Toll-like receptor 4 in Alzheimer's disease

doi:10.11817/j.issn.1673-9248.2023.04.017

Abstract

Abstract:

Alzheimer's disease (AD) is a degenerative disease of the central nervous system that mainly damages cognitive and memory functions. The pathogenesis of AD has not been fully elucidated. Recent studies have shown that neuroinflammatory response plays a key role in the pathogenesis of AD. As a trigger point of neuroinflammation in AD, Toll-like receptor 4 (TLR4) provides a potential target for the treatment of AD. This review aims to provide references for clinical treatment of AD.

Key words: Toll-like receptor 4, Alzheimer's disease, Neuroinflammation

Tianzi Liu, Baojun Wang. Research progress of Toll-like receptor 4 in Alzheimer's disease[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(04): 404-409.

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