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Chinese Journal of Cerebrovascular Diseases(Electronic Edition) ›› 2024, Vol. 18 ›› Issue (03): 277-280. doi: 10.11817/j.issn.1673-9248.2024.03.014

• Review • Previous Articles    

Current applications and future prospects of target trial emulation in the field of cerebrovascular diseases

Gaoting Ma1, Yingting Zuo1, Shaoyuan Lei1, Ran Mo1, Yifan Wu1, Shujuan Meng1, Ziying Jiang1, Yue Wu1, Yi Ren1, Pingping Wang1, Qian Zhang1, Qingfeng Ma1, Haiqing Song1, Lianmei Zhong1, Junwei Hao1,()   

  1. 1. Department of Neurology, Xuanwu Hospital Capital Medical University, Beijing 100053, China
  • Received:2024-01-03 Online:2024-06-01 Published:2024-07-29
  • Contact: Junwei Hao

Abstract:

Target trial emulation is a method that utilizes observational study data to simulate the outcomes of a randomized clinical trial. It has been widely applied in clinical research in recent years. The application of target trial emulation in the realm of cerebrovascular disease research can address the limitations inherent of randomized clinical trials, improve research efficiency and reliability, reduce experimental costs and time, and expand the sample size for better interpretability and generalizability of research findings. In the future, further development and refinement of target trial emulation in cerebrovascular disease research are essential to provide more robust scientific evidence for the treatment and prevention of cerebrovascular diseases. This article provides an overview of the current application and future prospects of target trial emulation in the field of cerebrovascular disease research.

Key words: Target trial emulation, Cerebrovascular disease, Randomized controlled trials

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