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中华脑血管病杂志(电子版) ›› 2022, Vol. 16 ›› Issue (01) : 48 -52. doi: 10.11817/j.issn.1673-9248.2022.01.010

综述

神经血管单元在脑小血管病中的研究进展
洪靖舒1, 韩登阳1, 郭向阳1,()   
  1. 1. 100191 北京大学第三医院麻醉科
  • 收稿日期:2020-12-10 出版日期:2022-02-01
  • 通信作者: 郭向阳
  • 基金资助:
    国家自然科学基金面上项目(82071189)

Neurovascular unit in cerebral small vessel disease: an update review

Jingshu Hong1, Dengyang Han1, Xiangyang Guo1,()   

  1. 1. Department of Anesthesiology, Peking University Third Hospital, Beijing 100191, China
  • Received:2020-12-10 Published:2022-02-01
  • Corresponding author: Xiangyang Guo
引用本文:

洪靖舒, 韩登阳, 郭向阳. 神经血管单元在脑小血管病中的研究进展[J/OL]. 中华脑血管病杂志(电子版), 2022, 16(01): 48-52.

Jingshu Hong, Dengyang Han, Xiangyang Guo. Neurovascular unit in cerebral small vessel disease: an update review[J/OL]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2022, 16(01): 48-52.

脑小血管病(CSVD)是指各种原因引发的脑小血管病变,并导致的一系列临床、影像学及病理改变的综合征。神经血管单元由神经元-胶质细胞-血管构成。近年来,随着对CSVD研究的不断深入,神经血管单元中不同细胞间的相互联系在CSVD中的作用也越来越受到关注。因此本文从神经血管单元角度阐明其各组成部分的相互作用在CSVD发生机制中的作用,为防范和治疗CSVD提供理论依据。

Cerebral small vessel disease (CSVD) is a disorder of cerebral small vessels caused by various reasons, resulting in a series of clinical, imaging and pathological changes. Neurovascular unit is composed by neurons-glial cells-cerebral blood vessels. In recent year, with the deeper understanding of CSVD pathogenesis, there has been an increasing interest in the role of the interaction among different components of neurovascular unit. Thus, this review comprehensively elucidates the role of the interaction among its components in the pathogenesis of CSVD, so as to provide theoretical basis for the prevention and treatment.

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