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中华脑血管病杂志(电子版)

中华脑血管病杂志(电子版) ›› 2022, Vol. 16 ›› Issue (01) : 44 -47. doi: 10.11817/j.issn.1673-9248.2022.01.009

综述

不同影像学表现的脑小血管病所致认知障碍特点的研究进展
张蓉1, 赵晨阳1, 何志义1,†()   
  1. 1. 110001　沈阳，中国医科大学附属第一医院神经内科
  • 收稿日期:2021-11-01 出版日期:2022-02-01
  • 通信作者: 何志义
  • 基金资助:
    国家自然科学基金面上项目(81971125)

Characteristics of cognitive impairment caused by cerebral small vascular disease with different imaging manifestations

Rong Zhang1, Chenyang Zhao1, Zhiyi He1,†()   

  1. 1. Department of Neurology, the First Affiliated Hospital of China Medical University, Shenyang 110001, China
  • Received:2021-11-01 Published:2022-02-01
  • Corresponding author: Zhiyi He
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张蓉, 赵晨阳, 何志义. 不同影像学表现的脑小血管病所致认知障碍特点的研究进展[J]. 中华脑血管病杂志(电子版), 2022, 16(01): 44-47.

Rong Zhang, Chenyang Zhao, Zhiyi He. Characteristics of cognitive impairment caused by cerebral small vascular disease with different imaging manifestations[J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2022, 16(01): 44-47.

脑小血管病是指影响颅内小动脉、小静脉和毛细血管等多种结构和功能的一组临床疾病。脑小血管病可无临床症状，但常与神经退行性疾病并存，可加重认知障碍，严重影响脑卒中的预后。脑小血管病是老年人认知障碍、情绪障碍和步态障碍的主要原因，其与认知障碍及血管性痴呆之间的关系已成为研究热点。降低认知障碍的发生率和进展是脑小血管病治疗或干预的关键临床目标之一。本文综述了不同影像学表现的脑小血管病所致认知障碍的特点，为延缓患者认知障碍的发生和发展提供依据。

关键词: 脑小血管病, 认知障碍, 脑白质高信号, 脑微出血

Cerebral small vessel disease (CSVD) is a group of clinical diseases that affect the structure and function of intracranial arterioles, small veins and capillaries. CSVD may present no clinical symptoms, but often coexists with neurodegenerative diseases, which can aggravate cognitive impairment and also seriously affect the prognosis of stroke. CSVD is the main cause of cognitive disorder, mood disorder and gait disorder in the elderly. Its relationship with cognitive impairment and vascular dementia has become a research hotspot. Reducing the incidence and progression of cognitive impairment is one of the key clinical goals of CSVD treatment and intervention. In this paper, the characteristics of cognitive impairment caused by CSVD with different imaging manifestations were reviewed to provide evidence for delaying the initiation and development of cognitive impairment in patients.

Key words: Cerebral small vessel disease, Cognitive impairment, White matter hyperintensity, Cerebral microbleed
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