切换至 "中华医学电子期刊资源库"

中华脑血管病杂志(电子版) ›› 2026, Vol. 20 ›› Issue (03) : 294 -300. doi: 10.3877/cma.j.issn.1673-9248.2026.03.009

临床研究

5G+智慧急救系统在急性大血管闭塞性缺血性脑卒中救治中的意义
刘心怡1, 林晓晖1, 陈荣城1, 林进皇1, 林定来1, 易婷玉1,(), 吴燕敏1, 陈文伙2,()   
  1. 1 363000 福建漳州,福建医科大学附属漳州市医院神内脑血管病介入科
    2 350001 福州,福建医科大学附属协和医院脑血管病介入科
  • 收稿日期:2026-02-06 出版日期:2026-06-01
  • 通信作者: 易婷玉, 陈文伙
  • 基金资助:
    福建省自然科学基金计划项目(2023J01122394)

Application value of 5G+ intelligent emergency system in the treatment of patients with acute large vessel occlusion ischemic stroke

Xinyi Liu1, Xiaohui Lin1, Rongcheng Chen1, Jinhuang Lin1, Dinglai Lin1, Tingyu Yi1,(), Yanmin Wu1, Wenhuo Chen2,()   

  1. 1 Department of Cerebral Vascular Disease Intervention, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou 363000, China
    2 Department of Cerebrovascular Disease Intervention, Fujian Medical University Union Hospital, Fuzhou 350001, China
  • Received:2026-02-06 Published:2026-06-01
  • Corresponding author: Tingyu Yi, Wenhuo Chen
引用本文:

刘心怡, 林晓晖, 陈荣城, 林进皇, 林定来, 易婷玉, 吴燕敏, 陈文伙. 5G+智慧急救系统在急性大血管闭塞性缺血性脑卒中救治中的意义[J/OL]. 中华脑血管病杂志(电子版), 2026, 20(03): 294-300.

Xinyi Liu, Xiaohui Lin, Rongcheng Chen, Jinhuang Lin, Dinglai Lin, Tingyu Yi, Yanmin Wu, Wenhuo Chen. Application value of 5G+ intelligent emergency system in the treatment of patients with acute large vessel occlusion ischemic stroke[J/OL]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2026, 20(03): 294-300.

目的

探讨5G+智慧急救系统在急性大血管闭塞性缺血性脑卒中患者救治中的应用效果。

方法

选取2022年1月1日至2024年3月1日在福建医科大学附属漳州市医院接受血管内治疗的患者,按照是否使用5G+智慧急救系统转运将患者分为5G转运组和非5G转运组。对比2组患者的救治时间(发病至血管穿刺时间、到院至血管穿刺时间、到院至血管开通时间和穿刺至血管开通时间)和90 d临床结局。采用Wilcoxon秩和检验比较2组患者救治时间的差异,采用Pearson χ2检验比较2组患者临床结局的差异。

结果

本研究共入组76例患者,其中5G转运组患者25例,非5G转运组患者51例。与非5G转运组患者相比,5G转运组患者的发病至血管穿刺时间[215.0(142.0,355.0)min vs 510.0(348.0,789.0)min]、到院至血管穿刺时间[24.0(19.5,26.0)min vs 91.0(79.0,112.5)min]、到院至血管开通时间[77.0(61.0,101.5)min vs 146.0(114.0,169.5)min]均明显缩短,差异均有统计学意义(Z=4.505、6.890、4.732,P均<0.001);2组患者的穿刺至血管开通时间比较,差异无统计学意义(P>0.05)。与非5G转运组患者相比,90 d后5G转运组患者的功能独立性更好(改良Rankin量表评分0~3分患者比例:68.00% vs 35.29%),症状性颅内出血率(0 vs 17.65%)和90 d内病死率(0 vs 33.33%)均更低,差异均有统计学意义(χ2=7.223、5.004、10.734,P=0.007、0.025、0.001)。

结论

5G+智慧急救系统通过优化脑卒中救治流程,有效缩短了救治时间,显著改善了急性大血管闭塞性缺血性脑卒中患者预后。

Objective

To explore the application effect of 5G+ intelligent emergency system in the treatment of patients with acute large vessel occlusion ischemic stroke.

Methods

The patients who received endovascular treatment in Zhangzhou Affiliated Hospital of Fujian Medical University from January 1, 2022 to March 1, 2024 were selected and divided into 5G transport group and non-5G transport group according to whether the 5G+ intelligent emergency system was used. The treatment time (onset-to-vascular puncture time, arrival-to-vascular puncture time, arrival-to-vascular recanalization time, puncture-to-vascular recanalization time) and clinical outcomes after 90 days were compared between the two groups. The Wilcoxon rank sum test was used for comparison of treatment time between groups. Pearson χ2 test was used for comparison of clinical outcomes between groups.

Results

A total of 76 patients were enrolled, including 25 patients in the 5G transport group and 51 patients in the non-5G transport group. Compared with the non-5G transport group, the time from onset to puncture in the 5G transport group was significantly shorter [215.0 (142.0, 355.0) min vs 510.0 (348.0, 789.0) min, Z=4.505, P<0.001], the time from arrival to vascular puncture was significantly shorter [24.0 (19.5, 26.0) min vs 91.0 (79.0, 112.5) min, Z=6.890, P<0.001], and the time from arrival to recanalization was significantly shorter [77.0 (61.0, 101.5) min vs 146.0 (114.0, 169.5) min, Z=4.732, P<0.001]. There was no significant difference in the time from puncture to vascular recanalization between the two groups (P>0.05). Functional independence was better in the 5G transport group than in the non-5G transport group after 90 days (modified Rankin scale score 0 - 3: 68.00% vs 35.29%, χ2=7.223, P=0.007), while the symptomatic intracranial hemorrhage rate (0 vs 17.65%, χ2=5.004, P=0.025) and 90-day mortality rate (0 vs 33.33%, χ2=10.734, P=0.001) were significantly lower.

Conclusion

The 5G+ intelligent emergency system can effectively shorten the treatment time and significantly improve the prognosis of patients with acute large vessel occlusive ischemic stroke by optimizing the treatment process of stroke.

图1 5G转运组与非5G转运组急性大血管闭塞性缺血性脑卒中患者转运流程对比
表1 5G转运组与非5G转运组急性大血管闭塞性缺血性脑卒中患者基线资料比较
表2 5G转运组与非5G转运组急性大血管闭塞性缺血性脑卒中患者救治时间比较[min,MQ1Q3)]
表3 5G转运组与非5G转运组急性大血管闭塞性缺血性脑卒中患者临床结局比较[例(%)]
图2 5G转运组与非5G转运组急性大血管闭塞性缺血性脑卒中患者90 d改良Rankin量表评分分布情况
1
Wang W, Jiang B, Sun H, et al. Prevalence, incidence, and mortality of stroke in China: results from a nationwide population-based survey of 480 687 adults [J]. Circulation, 2017, 135(8): 759-771.
2
Saver JL. Time is brain--quantified [J]. Stroke, 2006, 37(1): 263-266.
3
Goyal M, Jadhav AP, Bonafe A, et al. Analysis of workflow and time to treatment and the effects on outcome in endovascular treatment of acute ischemic stroke: results from the SWIFT PRIME randomized controlled trial [J]. Radiology, 2016, 279(3): 888-897.
4
中国老年医学学会急诊医学分会, 中华医学会急诊医学分会卒中学组, 中国卒中学会急救医学分会. 急性缺血性脑卒中急诊急救中国专家共识2018 [J]. 中国卒中杂志, 2018, 13(9): 956-967.
5
张运, 裴月红, 傅瑜. 急性缺血性卒中静脉溶栓治疗进展 [J/OL]. 中华脑血管病杂志(电子版), 2023, 17(2): 83-88.
6
Heldner MR, Zubler C, Mattle HP, et al. National Institutes of Health stroke scale score and vessel occlusion in 2152 patients with acute ischemic stroke [J]. Stroke, 2013, 44(4): 1153-1157.
7
Martinez-Gutierrez JC, Kim Y, Salazar-Marioni S, et al. Automated large vessel occlusion detection software and thrombectomy treatment times: a cluster randomized clinical trial [J]. JAMA Neurology, 2023, 80(11): 1182-1190.
8
Sarraj A, Goyal N, Chen M, et al. Direct to angiography vs repeated imaging approaches in transferred patients undergoing endovascular thrombectomy [J]. JAMA Neurology, 2021, 78(8): 916-926.
9
Aghaebrahim A, Streib C, Rangaraju S, et al. Streamlining door to recanalization processes in endovascular stroke therapy [J]. J Neurointerv Surg, 2017, 9(4): 340-345.
10
Radu RA, Gascou G, Machi P, et al. Current and future trends in acute ischemic stroke treatment: direct-to-angiography suite, middle vessel occlusion, large core, and minor strokes [J]. Eur J Radiol Open, 2023, 11: 100536.
11
Sun CHJ, Ribo M, Goyal M, et al. Door-to-puncture: a practical metric for capturing and enhancing system processes associated with endovascular stroke care, preliminary results from the rapid reperfusion registry [J]. J Am Heart Assoc, 2014, 3(2): e000859.
12
Mendez B, Requena M, Aires A, et al. Direct transfer to angio-suite to reduce workflow times and increase favorable clinical outcome: a case-control study [J]. Stroke, 2018, 49(11): 2723-2727.
13
Requena M, Olivé-Gadea M, Muchada M, et al. Direct to angiography suite without stopping for computed tomography imaging for patients with acute stroke: a randomized clinical trial [J]. JAMA Neurology, 2021, 78(9): 1099-1107.
14
Ribo M, Boned S, Rubiera M, et al. Direct transfer to angiosuite to reduce door-to-puncture time in thrombectomy for acute stroke [J]. J Neurointerv Surg, 2018, 10(3): 221-224.
15
Flores A, Seró L, Otto C, et al. Impact of prehospital stroke code in a public center in Paraguay: a pilot study [J]. Int J Stroke, 2019, 14(6): 646-649.
16
Venema E, Lingsma HF, Chalos V, et al. Personalized prehospital triage in acute ischemic stroke [J]. Stroke, 2019, 50(2): 313-320.
17
Waqas M, Vakharia K, Munich SA, et al. Initial emergency room triage of acute ischemic stroke [J]. Neurosurgery, 2019, 85(suppl_1): S38-S46.
18
Leifer D, Bravata DM, Connors JJB, et al. Metrics for measuring quality of care in comprehensive stroke centers: detailed follow-up to Brain Attack Coalition comprehensive stroke center recommendations: a statement for healthcare professionals from the American Heart Association/American Stroke Association [J]. Stroke, 2011, 42(3): 849-877.
19
Mohammaden MH, Doheim MF, Elfil M, et al. Direct to angiosuite versus conventional imaging in suspected large vessel occlusion: a systemic review and Meta-analysis [J]. Stroke, 2022, 53(8): 2478-2487.
20
Mazighi M, Meseguer E, Labreuche J, et al. Dramatic recovery in acute ischemic stroke is associated with arterial recanalization grade and speed [J]. Stroke, 2012, 43(11): 2998-3002.
21
Kaesmacher J, Maamari B, Meinel TR, et al. Effect of pre- and in-hospital delay on reperfusion in acute ischemic stroke mechanical thrombectomy [J]. Stroke, 2020, 51(10): 2934-2942.
22
Ribo M, Molina CA, Cobo E, et al. Association between time to reperfusion and outcome is primarily driven by the time from imaging to reperfusion [J]. Stroke, 2016, 47(4): 999-1004.
23
Zhou T, Li T, Zhu L, et al. One-stop stroke management platform reduces workflow times in patients receiving mechanical thrombectomy [J]. Front Neurol, 2022, 13: 1044347.
24
Requena M, Olivé M, García-Tornel Á, et al. Time matters: adjusted analysis of the influence of direct transfer to angiography-suite protocol in functional outcome [J]. Stroke, 2020, 51(6): 1766-1771.
25
Nair R, Rempel J, Khan K, et al. Direct to angiosuite in acute stroke with mobile stroke unit [J]. Can J Neurol Sci, 2024, 51(2): 226-232.
26
Galecio-Castillo M, Vivanco-Suarez J, Zevallos CB, et al. Direct to angiosuite strategy versus standard workflow triage for endovascular therapy: systematic review and Meta-analysis [J]. J Neurointerv Surg, 2023, 15(e1): e17-e25.
27
Li X, Li C, Zhou J, et al. Predictors of ninety-day mortality following mechanical thrombectomy for acute large vessel occlusion stroke [J]. Clin Neurol Neurosurg, 2022, 221: 107402.
28
Chen Y, Zhou S, Yang S, et al. Developing and predicting of early mortality after endovascular thrombectomy in patients with acute ischemic stroke [J]. Front Neurosci, 2022, 16: 1034472.
[1] 李运帷, 段晓春, 齐文涛. 重型颅脑损伤术后创伤性脑梗死的危险因素与发病机制研究进展[J/OL]. 中华神经创伤外科电子杂志, 2025, 11(06): 398-404.
[2] 宋丽娜, 安鹏. CTP跨时相放射组学模型预测急性脑梗死溶栓后出血转化风险[J/OL]. 中华脑科疾病与康复杂志(电子版), 2025, 15(06): 342-351.
[3] 李小萍, 张清芳, 李东霞, 陈文生, 王坤, 王诚婷, 龙建军. 基于HIF-1α/VEGF通路探讨经颅交流电刺激联合运动训练对脑梗死后肢体痉挛大鼠功能恢复的影响与机制研究[J/OL]. 中华脑科疾病与康复杂志(电子版), 2025, 15(05): 261-267.
[4] 朱华, 邓一军. 颈内动脉粥样硬化斑块的三维MR血管壁成像特征对急性脑梗死的预测效能研究[J/OL]. 中华介入放射学电子杂志, 2026, 14(01): 89-96.
[5] 张伟东, 谭斯奇, 马王志, 崔中馨, 李永宁. 血清S100、NSE联合IL-1β对脑梗死机械取栓术后脑损伤及预后评估[J/OL]. 中华介入放射学电子杂志, 2025, 13(04): 344-349.
[6] 吴波娜, 曹德峰, 吴婧. 急性小动脉闭塞型脑梗死患者血压昼夜节律改变与早期神经功能恶化的相关性研究[J/OL]. 中华卫生应急电子杂志, 2026, 12(01): 6-9.
[7] 郭祥林, 颜虎. 急诊绿色通道下阿替普酶与重组人组织型纤溶酶原激活剂溶栓救治急性脑梗死的效果比较研究[J/OL]. 中华卫生应急电子杂志, 2026, 12(01): 21-25.
[8] 王春伟, 杜青. 急性脑梗死患者THRIVE评分、NLR值、血清ACA、GFAP水平与静脉溶栓预后的相关性[J/OL]. 中华卫生应急电子杂志, 2025, 11(06): 325-328.
[9] 李丽娜, 彭滢, 巩俪, 郑志东. 血清脂蛋白(a)、载脂蛋白B/载脂蛋白A1比值与急性脑梗死阿替普酶静脉溶栓治疗预后的关系[J/OL]. 中华脑血管病杂志(电子版), 2026, 20(02): 178-184.
[10] 陈若梦, 苏旭东, 周晓伟, 张坤, 仇福成, 董慈, 陈子墨, 刘佳慧, 王浩然, 王红霞, 刘晓云. 脑机接口康复训练联合传统康复治疗对急性期脑梗死短期运动功能的改善效果[J/OL]. 中华脑血管病杂志(电子版), 2026, 20(02): 126-132.
[11] 于玲, 秦伟, 徐霁华, 胡秀朝, 杨磊, 胡文立. 急性小脑梗死的临床影像学特征[J/OL]. 中华脑血管病杂志(电子版), 2026, 20(02): 133-138.
[12] 钱海舟, 张珊珊, 殷琳玲, 吴智强, 汪露, 杨欢. 经颅多普勒超声在急性前循环大血管闭塞性脑梗死机械取栓后的应用价值[J/OL]. 中华脑血管病杂志(电子版), 2026, 20(01): 61-67.
[13] 张旭, 唐娟, 申婧, 杨琼, 高沛沛, 田苗苗, 马志翔, 姚恩生. 依达拉奉右莰醇联合阿替普酶动脉溶栓治疗急性脑梗死的临床疗效[J/OL]. 中华脑血管病杂志(电子版), 2025, 19(06): 490-495.
[14] 张伟东, 刘思婷, 黄蝶, 李永宁. 细胞焦亡介导脑梗死及脑缺血再灌注后脑组织损伤[J/OL]. 中华脑血管病杂志(电子版), 2025, 19(06): 519-525.
[15] 刘锦, 张婕, 刘松, 马丹, 韩剑虹. 2019—2022年昆明市二、三级医院卒中中心急性缺血性卒中静脉溶栓指标分析[J/OL]. 中华脑血管病杂志(电子版), 2025, 19(05): 397-403.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?